Suppr超能文献

转移因子对癌症患者活性玫瑰花结及白细胞游走的体外作用

In vitro effect of transfer factor on active rosettes and leucocyte migration of patients with cancer.

作者信息

Nékám K, Kalmár L, Gergely P, Kelemen G, Fekete B, Láng I, Lévai J, Petrányi G Y

出版信息

Clin Exp Immunol. 1977 Mar;27(3):416-20.

PMID:324669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1540949/
Abstract

The in vitro effect of transfer factor (TF) and its obtained by gel filtration was studied on the active rosettes and leucocyte migration inhibition. TF and one fraction (IV) restored the reactivity of lymphocytes from tumour-bearing patients to tuberculin and Candida antigens in the leucocyte migration assay. TF and fraction IV was also found to enhance the number of active rosettes of tumour-bearing patients, whereas no such effect was observed on lymphocytes of patients with active SLE or controls.

摘要

研究了转移因子（TF）及其经凝胶过滤得到的产物对活性玫瑰花结形成和白细胞迁移抑制的体外作用。在白细胞迁移试验中，TF和一个组分（IV）恢复了荷瘤患者淋巴细胞对结核菌素和念珠菌抗原的反应性。还发现TF和组分IV可增加荷瘤患者活性玫瑰花结的数量，而对活动性系统性红斑狼疮患者或对照者的淋巴细胞未观察到这种作用。

相似文献

1
In vitro effect of transfer factor on active rosettes and leucocyte migration of patients with cancer.转移因子对癌症患者活性玫瑰花结及白细胞游走的体外作用
Clin Exp Immunol. 1977 Mar;27(3):416-20.
2
The in vitro effect of thymic humoral factor and levamisole on peripheral blood lymphocytes in systemic lupus erythematosus patients.胸腺体液因子和左旋咪唑对系统性红斑狼疮患者外周血淋巴细胞的体外作用。
Clin Exp Immunol. 1978 Jan;31(1):111-5.
3
Human transfer factor in vitro. II. Augmentation of the secretion of leucocyte migration inhibitory factor (LIF) by leucocyte dialysate and by its components L-serine and glycine.人转移因子的体外研究。II. 白细胞透析液及其成分L-丝氨酸和甘氨酸对白细胞迁移抑制因子（LIF）分泌的增强作用。
Clin Exp Immunol. 1979 Jul;37(1):50-7.
4
Mononuclear phagocytes from patients with active systemic lupus erythematosus down-regulate the specific in vitro reactivity of autologous lymphocytes to double-stranded DNA.活动性系统性红斑狼疮患者的单核吞噬细胞可下调自体淋巴细胞对双链DNA的特异性体外反应性。
Clin Exp Immunol. 1988 Apr;72(1):43-9.
5
[Leukocyte migration inhibition test in lupus erythematosus and dermatomyositis].[红斑狼疮和皮肌炎中的白细胞迁移抑制试验]
Z Hautkr. 1977 Sep 1;52(17):906-12.
6
[Leukocyte migration inhibition and leukocyte adherence inhibition (LMI- and LAI-assay) in cancer patients by using preparations from human fetuses].[利用人胎儿制剂对癌症患者进行白细胞迁移抑制和白细胞黏附抑制（LMI和LAI检测）]
Acta Biol Med Ger. 1978;37(11-12):1747-57.
7
Effects of dialyzable leukocyte extracts with transfer factor activity on leukocyte migration in vitro. II. Separation and partial characterization of the components in DLE producing antigen-dependent and antigen-independent effects.具有转移因子活性的可透析白细胞提取物对体外白细胞迁移的影响。II. 产生抗原依赖性和抗原非依赖性效应的可透析白细胞提取物中各成分的分离及部分特性鉴定
J Lab Clin Med. 1979 May;93(5):819-37.
8
Cellular immune reactivity to nuclear antigens in systemic lupus erythematosus.
Acta Med Acad Sci Hung. 1976;33(1):41-50.
9
Enhanced propensity of T lymphocytes in patients with systemic lupus erythematosus to apoptosis in the presence of tumour necrosis factor alpha.在肿瘤坏死因子α存在的情况下，系统性红斑狼疮患者的T淋巴细胞凋亡倾向增强。
Scand J Rheumatol. 2009 Mar-Apr;38(2):112-20. doi: 10.1080/03009740802409496.
10
Effect of transfer factor on lymphocyte function in anergic patients.转移因子对无反应性患者淋巴细胞功能的影响。
J Clin Invest. 1972 Nov;51(11):2948-58. doi: 10.1172/JCI107119.

引用本文的文献

1
Rosette-increasing factor released by PHA-stimulated mononuclear cells in vitro which augments active E and EA rosette formation.体外由PHA刺激的单核细胞释放的玫瑰结增强因子，其可增强活性E和EA玫瑰结的形成。
Clin Exp Immunol. 1980 Jun;40(3):602-10.
2
Active E rosette formation by human lymphoblasts.人淋巴母细胞的活性E玫瑰花结形成
Immunology. 1978 Apr;34(4):721-4.

本文引用的文献

1
Human lymphocyte migration as a parameter of hypersensitivity.人类淋巴细胞迁移作为超敏反应的一个参数。
Acta Med Scand. 1967 Feb;181(2):247-56. doi: 10.1111/j.0954-6820.1967.tb07255.x.
2
Transfer factor.转移因子
Adv Immunol. 1969;11:195-266. doi: 10.1016/s0065-2776(08)60480-0.
3
Studies on the transfer factor of delayed hypersensitivity. Effect of dialysable leucocyte extracts from people of known tuberculin sensitivity on the migration of normal guinea-pig macrophages in the presence of antigen.迟发型超敏反应转移因子的研究。已知结核菌素敏感性人群的可透析白细胞提取物在有抗原存在时对正常豚鼠巨噬细胞迁移的影响。
Immunology. 1974 Jun;26(6):1069-80.
4
Restoration of T-lymphocyte deficiency with dialysable leucocyte extract.用可透析白细胞提取物恢复T淋巴细胞缺乏症。
Clin Exp Immunol. 1974 Feb;16(2):141-52.
5
Thymus-derived rosette-forming cells in various human disease states: cancer, lymphoma, bacterial and viral infections, and other diseases.处于各种人类疾病状态下的胸腺来源的玫瑰花结形成细胞：癌症、淋巴瘤、细菌和病毒感染以及其他疾病。
J Clin Invest. 1973 May;52(5):1026-32. doi: 10.1172/JCI107267.
6
Rosette-forming cells, immunologic deficiency diseases and transfer factor.成玫瑰花结细胞、免疫缺陷疾病与转移因子。
N Engl J Med. 1973 Apr 5;288(14):710-3. doi: 10.1056/NEJM197304052881405.
7
Transfer factor therapy in a case of complex immunodeficiency.
Cell Immunol. 1974 Mar 15;10(3):371-9. doi: 10.1016/0008-8749(74)90129-4.
8
Human T lymphocyte "E" rosette function. I. A process modulated by intracellular cyclic AMP.人T淋巴细胞“E”花环功能。I. 一个受细胞内环磷酸腺苷调节的过程。
J Exp Med. 1974 Oct 1;140(4):1122-6. doi: 10.1084/jem.140.4.1122.
9
In vitro transfer of cellular immunity against nasopharyngeal carcinoma using transfer factor from donors with Epstein-Barr virus antibody activity.利用具有EB病毒抗体活性供体的转移因子进行针对鼻咽癌的细胞免疫体外转移。
Cancer Res. 1974 Nov;34(11):3095-101.
10
Effect of transfer factor therapy on mixed lymphocyte culture reactivity.转移因子疗法对混合淋巴细胞培养反应性的影响。
Proc Natl Acad Sci U S A. 1974 Mar;71(3):867-71. doi: 10.1073/pnas.71.3.867.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验