转移因子对癌症患者活性玫瑰花结及白细胞游走的体外作用
In vitro effect of transfer factor on active rosettes and leucocyte migration of patients with cancer.
作者信息
Nékám K, Kalmár L, Gergely P, Kelemen G, Fekete B, Láng I, Lévai J, Petrányi G Y
出版信息
Clin Exp Immunol. 1977 Mar;27(3):416-20.
Abstract
The in vitro effect of transfer factor (TF) and its obtained by gel filtration was studied on the active rosettes and leucocyte migration inhibition. TF and one fraction (IV) restored the reactivity of lymphocytes from tumour-bearing patients to tuberculin and Candida antigens in the leucocyte migration assay. TF and fraction IV was also found to enhance the number of active rosettes of tumour-bearing patients, whereas no such effect was observed on lymphocytes of patients with active SLE or controls.
摘要
研究了转移因子（TF）及其经凝胶过滤得到的产物对活性玫瑰花结形成和白细胞迁移抑制的体外作用。在白细胞迁移试验中，TF和一个组分（IV）恢复了荷瘤患者淋巴细胞对结核菌素和念珠菌抗原的反应性。还发现TF和组分IV可增加荷瘤患者活性玫瑰花结的数量，而对活动性系统性红斑狼疮患者或对照者的淋巴细胞未观察到这种作用。
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引用本文的文献
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Active E rosette formation by human lymphoblasts.人淋巴母细胞的活性E玫瑰花结形成
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本文引用的文献
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Human lymphocyte migration as a parameter of hypersensitivity.人类淋巴细胞迁移作为超敏反应的一个参数。
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Transfer factor.转移因子
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