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基于纳米材料的伤口愈合疗法的最新进展

Recent Advances in Nanomaterial-Based Wound-Healing Therapeutics.

作者信息

Naskar Atanu, Kim Kwang-Sun

机构信息

Department of Chemistry and Chemistry Institute for Functional Materials, Pusan National University, Busan 46241, Korea.

出版信息

Pharmaceutics. 2020 May 30;12(6):499. doi: 10.3390/pharmaceutics12060499.

Abstract

Nanomaterial-based wound healing has tremendous potential for treating and preventing wound infections with its multiple benefits compared with traditional treatment approaches. In this regard, the physiochemical properties of nanomaterials enable researchers to conduct extensive studies on wound-healing applications. Nonetheless, issues concerning the use of nanomaterials in accelerating the efficacy of existing medical treatments remain unresolved. The present review highlights novel approaches focusing on the recent innovative strategies for wound healing and infection controls based on nanomaterials, including nanoparticles, nanocomposites, and scaffolds, which are elucidated in detail. In addition, the efficacy of nanomaterials as carriers for therapeutic agents associated with wound-healing applications has been addressed. Finally, nanomaterial-based scaffolds and their premise for future studies have been described. We believe that the in-depth analytical review, future insights, and potential challenges described herein will provide researchers an up-to-date reference on the use of nanomedicine and its innovative approaches that can enhance wound-healing applications.

摘要

与传统治疗方法相比,基于纳米材料的伤口愈合因其多种益处而在治疗和预防伤口感染方面具有巨大潜力。在这方面,纳米材料的物理化学性质使研究人员能够对伤口愈合应用进行广泛研究。尽管如此,关于使用纳米材料提高现有医疗治疗效果的问题仍未得到解决。本综述重点介绍了基于纳米材料(包括纳米颗粒、纳米复合材料和支架)的伤口愈合和感染控制的最新创新策略的新方法,并对其进行了详细阐述。此外,还讨论了纳米材料作为与伤口愈合应用相关的治疗剂载体的功效。最后,描述了基于纳米材料的支架及其未来研究的前提。我们相信,本文所述的深入分析性综述、未来见解和潜在挑战将为研究人员提供关于纳米医学及其创新方法的最新参考,这些方法可以增强伤口愈合应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/302f/7356512/11a59bec86c5/pharmaceutics-12-00499-g001.jpg

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