Liu Junxiu, Mozaffarian Dariush, Sy Stephen, Lee Yujin, Wilde Parke E, Abrahams-Gessel Shafika, Gaziano Tom, Micha Renata
Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA (J.L., D.M., Y.L., P.E.W., R.M.).
Brigham and Women's Hospital, Boston, MA (S.S., T.G.).
Circ Cardiovasc Qual Outcomes. 2020 Jun;13(6):e006313. doi: 10.1161/CIRCOUTCOMES.119.006313. Epub 2020 Jun 4.
Excess caloric intake is linked to weight gain, obesity, and related diseases, including type 2 diabetes mellitus and cardiovascular disease (CVD). Obesity incidence is rising, with nearly 3 in 4 US adults being overweight or obese. In 2018, the US federal government finalized the implementation of mandatory labeling of calorie content on all menu items across major chain restaurants nationally as a strategy to support informed consumer choice, reduce caloric intake, and potentially encourage restaurant reformulations. Yet, the potential health and economic impacts of this policy remain unclear.
We used a validated microsimulation model (CVD-PREDICT) to estimate reductions in CVD events, diabetes mellitus cases, gains in quality-adjusted life years, costs, and cost-effectiveness of the menu calorie labeling intervention, based on consumer responses alone, and further accounting for potential industry reformulation. The model incorporated nationally representative demographic and dietary data from National Health and Nutrition Examination Surveys 2009 to 2016; policy effects on consumer diets and body mass index-disease effects from published meta-analyses; and policy effects on industry reformulation, policy costs (policy administration, industry compliance, and reformulation), and health-related costs (formal and informal healthcare costs, productivity costs) from established sources or reasonable assumptions. We modeled change in calories to change in weight using an established dynamic weight-change model, assuming 50% of expected calorie reductions would translate to long-term reductions. Findings were evaluated over 5 years and a lifetime from healthcare and societal perspectives, with uncertainty incorporated in both 1-way and probabilistic sensitivity analyses. Between 2018 and 2023, implementation of the restaurant menu calorie labeling law was estimated, based on consumer response alone, to prevent 14 698 new CVD cases (including 1575 CVD deaths) and 21 522 new type 2 diabetes mellitus cases, gaining 8749 quality-adjusted life years. Over a lifetime, corresponding values were 135 781 new CVD cases (including 27 646 CVD deaths), 99 736 type 2 diabetes mellitus cases, and 367 450 quality-adjusted life years. Assuming modest restaurant item reformulation, both health and economic benefits were estimated to be about 2-fold larger than based on consumer response alone. The consumer response alone was estimated to be cost-saving by 2023, with net lifetime savings of $10.42B from a healthcare perspective and $12.71B from a societal perspective. Findings were robust in a range of sensitivity analyses.
Our national model suggests that the full implementation of the US calorie menu labeling law will generate significant health gains and healthcare and societal cost-savings. Industry responses to modestly reformulate menu items would provide even larger additional benefits.
热量摄入过多与体重增加、肥胖及相关疾病有关,包括2型糖尿病和心血管疾病(CVD)。肥胖发病率正在上升,美国近四分之三的成年人超重或肥胖。2018年,美国联邦政府最终确定在全国主要连锁餐厅的所有菜单项目上强制标注卡路里含量,作为支持消费者明智选择、减少热量摄入并可能鼓励餐厅重新配方的一项策略。然而,该政策潜在的健康和经济影响仍不明确。
我们使用了一个经过验证的微观模拟模型(CVD-PREDICT),仅基于消费者反应,并进一步考虑潜在的行业重新配方,来估计菜单卡路里标注干预在心血管疾病事件减少、糖尿病病例、质量调整生命年增加、成本以及成本效益方面的情况。该模型纳入了2009年至2016年全国健康与营养检查调查中具有全国代表性的人口统计学和饮食数据;已发表的荟萃分析中政策对消费者饮食和体重指数疾病的影响;以及既定来源或合理假设下政策对行业重新配方、政策成本(政策管理、行业合规和重新配方)和健康相关成本(正规和非正规医疗成本、生产力成本)的影响。我们使用一个既定的动态体重变化模型,将卡路里变化建模为体重变化,假设预期卡路里减少的50%将转化为长期减少。从医疗保健和社会角度,在5年和一生的时间范围内对结果进行评估,并在单向和概率敏感性分析中纳入不确定性。仅基于消费者反应估计,在2018年至2023年期间,餐厅菜单卡路里标注法的实施将预防14698例新的心血管疾病病例(包括1575例心血管疾病死亡)和21522例新的2型糖尿病病例,获得8749个质量调整生命年。在一生中,相应的值为135781例新的心血管疾病病例(包括27646例心血管疾病死亡)、99736例2型糖尿病病例和367450个质量调整生命年。假设餐厅菜品进行适度重新配方,估计健康和经济效益均比仅基于消费者反应时大约高出一倍。仅消费者反应估计到2023年可节省成本,从医疗保健角度净节省104.2亿美元,从社会角度净节省127.1亿美元。在一系列敏感性分析中,结果都很稳健。
我们的全国性模型表明,美国卡路里菜单标注法的全面实施将带来显著的健康益处,并节省医疗保健和社会成本。行业对菜单项目进行适度重新配方的反应将带来更大的额外益处。