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机器人辅助食管癌根治术中预防胸内喉返神经损伤。

Prevention of intra-thoracic recurrent laryngeal nerve injury with robot-assisted esophagectomy.

机构信息

Department of Upper Gastrointestinal Surgery, Kitasato University School of Medicine, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan.

Division of Advanced Surgical Oncology, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Japan.

出版信息

Langenbecks Arch Surg. 2020 Jun;405(4):533-540. doi: 10.1007/s00423-020-01904-0. Epub 2020 Jun 3.

Abstract

PURPOSE

Transthoracic esophagectomy for esophageal cancer is one of the most invasive procedures in surgery for gastrointestinal cancer. Serious complications sometimes occur after esophageal cancer surgery, including recurrent laryngeal nerve injury and pneumonia. The purpose of this study was to access the possibility of robot-assisted thoracoscopic esophagectomy for esophageal cancer in terms of preventing recurrent laryngeal nerve injury.

METHODS

Operations in thoracic part were performed in prone position with bilateral ventilation. During dissection of the recurrent laryngeal nerve lymph nodes, thin blood vessels were coagulated with Maryland bipolar forceps in the left hand and then dissected with monopolar scissors in the right hand. Especially when dissecting left recurrent laryngeal nerve lymph nodes, the nerve was left unisolated from the vascular sheath that involves the aortic arch. Short-term outcomes including operative time, estimated blood loss, and postoperative complications including recurrent laryngeal nerve injury were accessed.

RESULTS

From November 2018 to January 2020, 20 patients underwent robot-assisted thoracoscopic esophagectomy for esophageal cancer. Thoracic operative time was 242 min, estimated blood loss in the thoracic part was minimal, the number of dissected mediastinal lymph nodes was 19 (all median), and the incidence rates of recurrent laryngeal nerve injury and pneumonia were 10% (2 case) and 10% (2 cases), respectively.

CONCLUSION

Robot-assisted thoracoscopic esophagectomy for esophageal cancer has the possibility of reducing recurrent laryngeal nerve injury even in the introductory period. Randomized controlled trials are required to confirm this advantage of the robotic surgery.

摘要

目的

胸腹腔镜食管癌切除术是胃肠道癌症手术中最具侵袭性的手术之一。食管癌手术后有时会发生严重的并发症,包括喉返神经损伤和肺炎。本研究旨在探讨机器人辅助胸腔镜食管癌切除术在预防喉返神经损伤方面的可能性。

方法

手术在胸部采用双侧通气的俯卧位进行。在喉返神经淋巴结解剖过程中,左手用 Maryland 双极镊子夹住细血管,然后用右手的单极剪刀解剖。特别是在解剖左侧喉返神经淋巴结时,神经未与包含主动脉弓的血管鞘分离。评估手术时间、估计出血量和术后并发症,包括喉返神经损伤。

结果

2018 年 11 月至 2020 年 1 月,20 例患者接受了机器人辅助胸腔镜食管癌切除术。胸腔手术时间为 242 分钟,胸部估计出血量最少,纵隔淋巴结清扫数量为 19 个(均为中位数),喉返神经损伤和肺炎的发生率分别为 10%(2 例)和 10%(2 例)。

结论

即使在介绍阶段,机器人辅助胸腔镜食管癌切除术也有可能减少喉返神经损伤。需要进行随机对照试验来证实机器人手术的这一优势。

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