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Risk of nosocomial transmission of coronavirus disease 2019: an experience in a general ward setting in Hong Kong.2019 年冠状病毒病在医院环境中的传播风险:香港普通病房的经验。
J Hosp Infect. 2020 Jun;105(2):119-127. doi: 10.1016/j.jhin.2020.03.036. Epub 2020 Apr 4.
2
COVID-19 may transmit through aerosol.新型冠状病毒肺炎可能通过气溶胶传播。
Ir J Med Sci. 2020 Nov;189(4):1143-1144. doi: 10.1007/s11845-020-02218-2. Epub 2020 Mar 24.
3
Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic.心血管考虑因素在 COVID-19 大流行期间的患者、医护人员和卫生系统。
J Am Coll Cardiol. 2020 May 12;75(18):2352-2371. doi: 10.1016/j.jacc.2020.03.031. Epub 2020 Mar 19.
4
The impact of high-flow nasal cannula (HFNC) on coughing distance: implications on its use during the novel coronavirus disease outbreak.高流量鼻导管(HFNC)对咳嗽距离的影响:对其在新型冠状病毒病疫情期间使用的启示。
Can J Anaesth. 2020 Jul;67(7):893-894. doi: 10.1007/s12630-020-01634-3. Epub 2020 Mar 18.
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Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1.与严重急性呼吸综合征冠状病毒1(SARS-CoV-1)相比,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)在气溶胶和表面的稳定性
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Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures.新型冠状病毒肺炎(COVID-19)具有独特的流行病学和临床特征,提示应采取特殊的控制措施。
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产生气溶胶的程序和 SARS-CoV-2 对医护人员的感染风险:证据的局限性。

Aerosol-generating procedures and infective risk to healthcare workers from SARS-CoV-2: the limits of the evidence.

机构信息

Sunshine Coast Hospital and Health Service, Queensland, Australia.

School of Social and Political Sciences, The University of Sydney, New South Wales, Australia.

出版信息

J Hosp Infect. 2020 Aug;105(4):717-725. doi: 10.1016/j.jhin.2020.05.037. Epub 2020 Jun 1.

DOI:10.1016/j.jhin.2020.05.037
PMID:32497651
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7263217/
Abstract

The transmission behaviour of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is still being defined. It is likely that it is transmitted predominantly by droplets and direct contact and it is possible that there is at least opportunistic airborne transmission. In order to protect healthcare staff adequately it is necessary that we establish whether aerosol-generating procedures (AGPs) increase the risk of transmission of SARS-CoV-2. Where we do not have evidence relating to SARS-CoV-2, guidelines for safely conducting these procedures should consider the risk of transmitting related pathogens. Currently there is very little evidence detailing the transmission of SARS-CoV-2 associated with any specific procedures. Regarding AGPs and respiratory pathogens in general, there is still a large knowledge gap that will leave clinicians unsure of the risk to themselves when offering these procedures. This review aimed to summarize the evidence (and gaps in evidence) around AGPs and SARS-CoV-2.

摘要

严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)的传播行为仍在确定中。它很可能主要通过飞沫和直接接触传播,也可能存在至少偶发的空气传播。为了充分保护医护人员,我们有必要确定是否产生气溶胶的操作(AGPs)会增加 SARS-CoV-2 传播的风险。对于没有 SARS-CoV-2 相关证据的情况,安全进行这些操作的指南应考虑传播相关病原体的风险。目前,详细说明与任何特定操作相关的 SARS-CoV-2 传播的证据非常少。关于 AGPs 和一般呼吸道病原体,仍存在很大的知识空白,这将使临床医生在提供这些操作时不确定自身的风险。本综述旨在总结有关 AGPs 和 SARS-CoV-2 的证据(和证据空白)。