Sunshine Coast Hospital and Health Service, Queensland, Australia.
School of Social and Political Sciences, The University of Sydney, New South Wales, Australia.
J Hosp Infect. 2020 Aug;105(4):717-725. doi: 10.1016/j.jhin.2020.05.037. Epub 2020 Jun 1.
The transmission behaviour of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is still being defined. It is likely that it is transmitted predominantly by droplets and direct contact and it is possible that there is at least opportunistic airborne transmission. In order to protect healthcare staff adequately it is necessary that we establish whether aerosol-generating procedures (AGPs) increase the risk of transmission of SARS-CoV-2. Where we do not have evidence relating to SARS-CoV-2, guidelines for safely conducting these procedures should consider the risk of transmitting related pathogens. Currently there is very little evidence detailing the transmission of SARS-CoV-2 associated with any specific procedures. Regarding AGPs and respiratory pathogens in general, there is still a large knowledge gap that will leave clinicians unsure of the risk to themselves when offering these procedures. This review aimed to summarize the evidence (and gaps in evidence) around AGPs and SARS-CoV-2.
严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)的传播行为仍在确定中。它很可能主要通过飞沫和直接接触传播,也可能存在至少偶发的空气传播。为了充分保护医护人员,我们有必要确定是否产生气溶胶的操作(AGPs)会增加 SARS-CoV-2 传播的风险。对于没有 SARS-CoV-2 相关证据的情况,安全进行这些操作的指南应考虑传播相关病原体的风险。目前,详细说明与任何特定操作相关的 SARS-CoV-2 传播的证据非常少。关于 AGPs 和一般呼吸道病原体,仍存在很大的知识空白,这将使临床医生在提供这些操作时不确定自身的风险。本综述旨在总结有关 AGPs 和 SARS-CoV-2 的证据(和证据空白)。