El-Wahsh S, Bogaardt H, Kumfor F, Ballard K
Discipline of Speech Pathology, Faculty of Medicine and Health, The University of Sydney, 75 East Street, Lidcombe, NSW, 2141, Australia.
The University of Sydney, Brain and Mind Centre and School of Psychology, 94 Mallett St, Camperdown, NSW, 2050.
Mult Scler Relat Disord. 2020 Aug;43:102206. doi: 10.1016/j.msard.2020.102206. Epub 2020 May 26.
There is growing recognition that communication and language can be compromised in persons with multiple sclerosis (MS). However, patient-reported outcome measures (PROMs) designed to measure communication and language function in MS are currently lacking.
This study aimed to develop and validate a novel PROM, the Communication and Language Assessment questionnaire for persons with Multiple Sclerosis (CLAMS).
One-hundred and ninety-nine participants were recruited internationally through online channels. Participants completed an online questionnaire consisting of 41-items generated from the: (1) La Trobe Communication Questionnaire (LCQ), (2) Speech pathology-specific questionnaire for persons with Multiple Sclerosis (SMS), and (3) published research describing communication and language in MS. These items were then submitted to preliminary psychometric evaluation, including principal component analysis, internal consistency, test-retest reliability, criterion validity, and analyses of floor and ceiling effects. Criterion validity was assessed by comparing the CLAMS with the Communication Participation Item Bank (CPIB).
The final CLAMS contained 11-items. Internal consistency was high (α = 0.944) and test-retest reliability. All items produced an intra-class correlation coefficient ≥ 0.70. No floor or ceiling effects were present. A statistically significant strong correlation between the CLAMS and the CPIB was identified (r = -0.750, p = ≤ 0.001).
The CLAMS is a reliable and valid PROM that assesses self-perceived communication and language function in MS. This tool can be used for research and clinical purposes to measure intervention outcomes, monitor symptom evolution, evaluate service delivery, facilitate patient-centred care, and as an adjunct to clinical assessment.
人们越来越认识到，多发性硬化症（MS）患者的沟通和语言能力可能会受到损害。然而，目前缺乏旨在测量MS患者沟通和语言功能的患者报告结局指标（PROMs）。
本研究旨在开发并验证一种新型的PROM，即多发性硬化症患者沟通与语言评估问卷（CLAMS）。
通过在线渠道在国际范围内招募了199名参与者。参与者完成了一份在线问卷，该问卷由41个项目组成，这些项目来自：（1）拉筹伯沟通问卷（LCQ），（2）针对多发性硬化症患者的言语病理学特定问卷（SMS），以及（3）描述MS患者沟通和语言的已发表研究。然后将这些项目提交给初步的心理测量学评估，包括主成分分析、内部一致性、重测信度、效标效度以及地板效应和天花板效应分析。通过将CLAMS与沟通参与项目库（CPIB）进行比较来评估效标效度。
最终的CLAMS包含11个项目。内部一致性较高（α = 0.944）且重测信度良好。所有项目的组内相关系数均≥ 0.70。不存在地板效应或天花板效应。CLAMS与CPIB之间存在统计学上显著的强相关性（r = -0.750，p = ≤ 0.001）。
CLAMS是一种可靠且有效的PROM，可评估MS患者自我感知的沟通和语言功能。该工具可用于研究和临床目的，以测量干预结果、监测症状演变、评估服务提供情况、促进以患者为中心的护理，并作为临床评估的辅助手段。
