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呼吸足矣:仅通过呼吸即可传播流感病毒和 SARS-CoV-2。

Breathing Is Enough: For the Spread of Influenza Virus and SARS-CoV-2 by Breathing Only.

机构信息

GS Bio-Inhalation GmbH, Headquarters & Logistics, Gemuenden, Germany.

出版信息

J Aerosol Med Pulm Drug Deliv. 2020 Aug;33(4):230-234. doi: 10.1089/jamp.2020.1616. Epub 2020 Jun 17.

DOI:10.1089/jamp.2020.1616
PMID:32552296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7406993/
Abstract

The transmission of respiratory viruses such as influenza and corona viruses from one person to another is still not fully understood. A literature search showed that there is a strong scientific rationale and evidence that viruses are very efficiently spread through aerosols by the patient's breathing only. It is not necessary for the patient to cough or sneeze. The exhaled aerosol particles are generated by normal breathing in the deep lung through reopening of collapsed small airways during inspiration. These mucus/surfactant aerosols (size range between 0.2 and 0.6 μm) can transport viruses out of the lungs of patients and be present in the room air for hours. These aerosol particles are difficult to filter out of the air; because of their physical properties, new strategies must be developed to protect people from these virus aerosols.

摘要

呼吸道病毒(如流感病毒和冠状病毒)在人与人之间的传播仍不完全清楚。文献检索表明,有强有力的科学依据和证据表明,病毒通过患者的呼吸非常有效地以气溶胶形式传播,而患者无需咳嗽或打喷嚏。呼出的气溶胶颗粒是通过在吸气过程中小气道重新开放时从深肺正常呼吸产生的。这些粘液/表面活性剂气溶胶(大小范围在 0.2 至 0.6μm 之间)可以将病毒从患者的肺部运出,并在室内空气中存在数小时。这些气溶胶颗粒很难从空气中过滤掉;由于其物理特性,必须开发新的策略来保护人们免受这些病毒气溶胶的侵害。

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本文引用的文献

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Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals.SARS-CoV-2 的空气动力学分析在两家武汉医院进行。
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Impact of Health on Particle Size of Exhaled Respiratory Aerosols: Case-control Study.健康对呼出呼吸道气溶胶粒径的影响:病例对照研究。
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Airborne transmission of SARS-CoV-2: The world should face the reality.空气传播 SARS-CoV-2:全世界应正视现实。
Environ Int. 2020 Jun;139:105730. doi: 10.1016/j.envint.2020.105730. Epub 2020 Apr 10.
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Effectiveness of Surgical and Cotton Masks in Blocking SARS-CoV-2: A Controlled Comparison in 4 Patients.手术口罩和棉质口罩对新型冠状病毒的防护效果:4例患者的对照比较
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