National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People's Republic of China; Chinese Center for Tropical Diseases Research, Shanghai, People's Republic of China; WHO Collaborating Centre for Tropical Diseases, Shanghai, People's Republic of China; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, People's Republic of China; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai, People's Republic of China.
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, People's Republic of China; Chinese Center for Tropical Diseases Research, Shanghai, People's Republic of China; WHO Collaborating Centre for Tropical Diseases, Shanghai, People's Republic of China; National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai, People's Republic of China; Key Laboratory of Parasite and Vector Biology, Ministry of Health, Shanghai, People's Republic of China.
Adv Parasitol. 2020;110:63-105. doi: 10.1016/bs.apar.2020.03.005. Epub 2020 Apr 30.
Although the past decades have seen a remarkable decrease in malaria-caused mortality and morbidity, the infection remains a significant challenge to global health. In the battle against malaria, China has gained notable feat and achievement since the 1940s through the efforts of several generations. Notably, China has not recorded a single indigenous malaria case since August 2016. The National Institute of Parasitic Diseases of the Chinese Center for Disease Control and Prevention (NIPD), as the only specialized institution for parasitic disease at the national level, has played a significant role in the malaria control, prevention, and elimination in China in the different historical periods. In order to transfer Chinese experiences on malaria control and elimination to other Low and Middle Income Countries (LMICs) and to improve global health collaboration, we have summarized and reviewed the contributions and achievements by the NIPD over the past 70 years, covering the epidemic situation; field investigation and laboratory experimental research on both parasite and vector; research and development on diagnostics, drugs, and insecticides; surveillance and response; technical and international. Support and cooperation. In addition, we also focus in particular on malaria retransmission risk, strategies on management of imported malaria cases and mobile populations, surveillance and response capacity to be maintained in post-elimination stage, challenges on diagnosis, drug resistance, and insecticide resistance as future concerns.
尽管过去几十年疟疾导致的死亡率和发病率显著下降,但这种感染仍然是全球健康的重大挑战。在中国,自 20 世纪 40 年代以来,经过几代人的努力,在抗击疟疾方面取得了显著的成就。值得注意的是,自 2016 年 8 月以来,中国已连续 4 年无本地感染疟疾病例报告。中国疾病预防控制中心寄生虫病预防控制所(以下简称寄生虫病所)作为国家级寄生虫病专业防治机构,在不同历史时期都为我国疟疾的防控和消除工作做出了重要贡献。为了向其他中低收入国家(LMICs)转移中国在疟疾防控和消除方面的经验,加强全球卫生合作,我们总结和回顾了寄生虫病所在过去 70 年中的贡献和成就,涵盖了疫情、寄生虫和媒介的现场调查和实验室实验研究、诊断试剂、药物和杀虫剂的研发、监测和反应、技术和国际支持与合作。此外,我们还特别关注消除后的再传播风险、输入性疟疾病例和流动人口的管理策略、消除阶段要保持的监测和反应能力、诊断、耐药性和抗药性等未来关注的挑战。