Deng Qian, Li Xiao Xue, Fang Yanting, Chen Xin, Xue Jingui
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Evid Based Complement Alternat Med. 2020 Jun 4;2020:5926381. doi: 10.1155/2020/5926381. eCollection 2020.
Atherosclerotic cardiovascular disease (ASCVD) is one of the diseases with the highest morbidity and mortality globally. It causes a huge burden on families and caregivers and high costs for medicine and surgical interventions. Given expensive surgeries and failures of most conventional treatments, medical community tries to find a more cost-effective cure. Thus, attentions have been primarily focused on food or herbs. Quercetin (Qu) extracted from food, a flavonoid component, develops potentials of alternative or complementary medicine in atherosclerosis. Due to the wide range of health benefits, researchers have considered to apply Qu as a natural compound in therapy. This review is aimed to identify the antiatherosclerosis functions of Qu in treating ASCVD such as anti-inflammatory, antioxidant properties, effects on endothelium-dependent vasodilation, and blood lipid-lowering.
动脉粥样硬化性心血管疾病（ASCVD）是全球发病率和死亡率最高的疾病之一。它给家庭和护理人员带来了巨大负担，也给药物和手术干预带来了高昂成本。鉴于手术费用高昂且大多数传统治疗方法效果不佳，医学界试图寻找一种更具成本效益的治疗方法。因此，注意力主要集中在食物或草药上。从食物中提取的槲皮素（Qu）是一种黄酮类成分，在动脉粥样硬化中具有替代或补充医学的潜力。由于其广泛的健康益处，研究人员已考虑将Qu作为一种天然化合物用于治疗。本综述旨在确定Qu在治疗ASCVD中的抗动脉粥样硬化功能，如抗炎、抗氧化特性、对内皮依赖性血管舒张的影响以及降血脂作用。
