Thayer School of Engineering, Dartmouth College, Hanover, NH, 03755, USA.
Thayer School of Engineering and Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.
Med Phys. 2020 Sep;47(9):3861-3869. doi: 10.1002/mp.14353. Epub 2020 Jul 18.
To demonstrate the potential benefits of remote camera-based scintillation imaging for routine quality assurance (QA) measurements for magnetic resonance guided radiotherapy (MRgRT) linear accelerators.
A wall-mounted CMOS camera with a time-synchronized intensifier was used to image photons produced from a scintillation screen in response to dose deposition from a 6 MV FFF x-ray beam produced by a 0.35 T MR-linac. The oblique angle of the field of view was corrected using a projective transform from a checkerboard calibration target. Output sensitivity and constancy was measured using the scintillator and benchmarked against an A28 ion chamber. Field cross-plane and in-plane profiles were measured for field sizes ranging from 1.68 × 1.66 cm to 20.02 × 19.92 cm with both scintillation imaging and using an IC profiler. Multileaf collimator (MLC) shifts were introduced to test sensitivity of the scintillation imaging system to small spatial deviations. A picket fence test and star-shot were delivered to both the scintillator and EBT3 film to compare accuracy in measuring MLC positions and isocenter size.
The scintillation imaging system showed comparable sensitivity and linearity to the ion chamber in response to changes in machine output down to 0.5 MU (R = 0.99). Cross-plane profiles show strong agreement with defined field sizes using full width half maximum (FWHM) measurement of <2 mm for field sizes below 15 cm, but the oblique viewing angle was the limiting factor in accuracy of in-plane profile widths. However, the system provided high-resolution profiles in both directions for constancy measurements. Small shifts in the field position down to 0.5 mm were detectable with <0.1 mm accuracy. Multileaf collimator positions as measured with both scintillation imaging and EBT3 film were measured within ± 1 mm tolerance and both detection systems produced similar isocenter sizes from the star-shot analysis (0.81 and 0.83 mm radii).
Remote scintillation imaging of a two-dimensional screen provided a rapid, versatile, MR-compatible solution to many routine quality assurance procedures including output constancy, profile flatness and symmetry constancy, MLC position verification and isocenter size. This method is high-resolution, does not require post-irradiation readout, and provides simple, instantaneous data acquisition. Full automation of the readout and processing could make this a very simple but effective QA tool, and is adaptable to all medical accelerators.
展示基于远程相机闪烁体成像技术在磁共振引导放射治疗(MRgRT)直线加速器常规质量保证(QA)测量中的潜在优势。
使用壁装式 CMOS 相机和时同步增强器,对闪烁屏响应 6MVFFFx 射线束剂量沉积产生的光子进行成像,该 x 射线束由 0.35T 的 MR 直线加速器产生。通过来自棋盘格校准靶的射影变换校正视场的倾斜角。使用闪烁体和基准 A28 离子室测量输出灵敏度和稳定性。使用闪烁成像和 IC 轮廓仪测量从 1.68×1.66cm 到 20.02×19.92cm 的各种射野的跨平面和平面内射野轮廓。引入多叶准直器(MLC)位移,以测试闪烁成像系统对小空间偏差的灵敏度。对闪烁体和 EBT3 胶片进行尖桩围栏测试和星状测试,以比较测量 MLC 位置和等中心大小的准确性。
闪烁成像系统在响应机器输出变化方面表现出与离子室相当的灵敏度和线性度,低至 0.5MU(R=0.99)。使用全宽半高(FWHM)测量,对于小于 15cm 的射野,横平面轮廓与定义的射野大小具有很强的一致性,<2mm,但倾斜视角是平面内轮廓宽度准确性的限制因素。然而,该系统为恒定性测量提供了两个方向的高分辨率轮廓。小至 0.5mm 的场位置位移可通过<0.1mm 的精度进行检测。使用闪烁成像和 EBT3 胶片测量的多叶准直器位置在±1mm 的容差范围内,并且两个检测系统都从星状分析中产生了相似的等中心大小(0.81 和 0.83mm 半径)。
二维屏幕的远程闪烁体成像提供了一种快速、多功能、与磁共振兼容的解决方案,适用于许多常规质量保证程序,包括输出稳定性、轮廓平整度和对称性稳定性、MLC 位置验证和等中心大小。该方法分辨率高,不需要辐照后读出,并且提供简单、即时的数据采集。如果实现读取和处理的完全自动化,这可能成为一种非常简单但有效的 QA 工具,并且适用于所有医用加速器。