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美国的原生性恰加斯病:人们是如何感染的?

Autochthonous Chagas Disease in the United States: How Are People Getting Infected?

机构信息

1Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida.

2Emerging Pathogens Institute, University of Florida, Gainesville, Florida.

出版信息

Am J Trop Med Hyg. 2020 Sep;103(3):967-969. doi: 10.4269/ajtmh.19-0733.

DOI:10.4269/ajtmh.19-0733
PMID:32602437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7470559/
Abstract

In the United States, Chagas disease is diagnosed in less than 1% of the estimated > 300,000 people who have the disease. However, the actual prevalence remains unknown, and these estimates may be wide of the mark (too high or too low). The greater part of those living with the disease acquired the infection in an endemic region of Latin America, but autochthonous transmission in the United States is increasingly being described. These cases are considered rare, and the transmission routes are largely unknown. Although triatomines or "kissing bugs" harbor in North America, most autochthonous cases are presumed rather than confirmed exposures to naturally infected kissing bugs. Public knowledge of Chagas is growing, and efforts are underway to provide greater awareness, but what are the risk factors for human transmission of Chagas disease in the United States?

摘要

在美国,估计有超过 30 万人患有该病,但只有不到 1%的人被诊断出患有这种疾病。然而,实际的患病率仍不清楚,这些估计可能相差甚远(过高或过低)。大多数患有该病的人是在拉丁美洲的一个流行地区感染的,但该病在美国的本土传播也越来越多。这些病例被认为是罕见的,其传播途径也大多未知。尽管在北美的有蛰针的猎蝽或“接吻虫”(也称锥蝽)携带这种寄生虫,但大多数本土病例都只是假定的,而不是经证实的与自然感染的接吻虫接触。公众对恰加斯病的认识正在提高,并且正在努力提高认识,但在美国,恰加斯病的人类传播的危险因素有哪些?

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