Sutherland G R, Baker E, Callen D F, Hyland V J, Wong G, Clark S, Jones S S, Eglinton L K, Shannon M F, Lopez A F
Cytogenetics Unit, Adelaide Children's Hospital, North Adelaide, S.A., Australia.
Hum Genet. 1988 Aug;79(4):335-7. doi: 10.1007/BF00282171.
DNA probes to the human interleukin 4 (IL4) and interleukin 6 (IL6) genes have been used for in situ hybridization to normal human chromosomes and Southern blot analysis of a series of mouse-human hybrid cell lines. IL4 maps to 5q31, the same location as IL5 and other haemopoietic growth factor genes. IL6 maps to 7p15. The significance of these locations is discussed.
用于人类白细胞介素4（IL4）和白细胞介素6（IL6）基因的DNA探针已被用于对正常人染色体进行原位杂交以及对一系列小鼠-人杂交细胞系进行Southern印迹分析。IL4定位于5q31，与IL5和其他造血生长因子基因位于同一位置。IL6定位于7p15。文中讨论了这些定位的意义。
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