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本文引用的文献

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Automated stent coverage analysis in intravascular OCT (IVOCT) image volumes using a support vector machine and mesh growing.使用支持向量机和网格生长技术对血管内光学相干断层扫描(IVOCT)图像容积进行自动支架覆盖分析。
Biomed Opt Express. 2019 May 16;10(6):2809-2828. doi: 10.1364/BOE.10.002809. eCollection 2019 Jun 1.
2
Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity.冠状动脉光学相干断层成像衍生的血流储备分数评估冠状动脉狭窄严重程度的诊断准确性。
EuroIntervention. 2019 Jun 20;15(2):189-197. doi: 10.4244/EIJ-D-19-00182.
3
First Presentation of Integration of Intravascular Optical Coherence Tomography and Computational Fractional Flow Reserve.
Int J Cardiovasc Imaging. 2019 Apr;35(4):601-602. doi: 10.1007/s10554-018-1491-1. Epub 2018 Nov 2.
4
2018 ESC/EACTS Guidelines on myocardial revascularization.2018年欧洲心脏病学会/欧洲心胸外科学会心肌血运重建指南。
Eur Heart J. 2019 Jan 7;40(2):87-165. doi: 10.1093/eurheartj/ehy394.
5
Clinical use of intracoronary imaging. Part 1: guidance and optimization of coronary interventions. An expert consensus document of the European Association of Percutaneous Cardiovascular Interventions.冠状动脉内影像学的临床应用。第 1 部分:冠状动脉介入治疗的指导和优化。欧洲经皮心血管介入治疗协会的专家共识文件。
Eur Heart J. 2018 Sep 14;39(35):3281-3300. doi: 10.1093/eurheartj/ehy285.
6
Characteristics of early versus late in-stent restenosis in second-generation drug-eluting stents: an optical coherence tomography study.第二代药物洗脱支架中早期与晚期支架内再狭窄的特点:光学相干断层成像研究。
EuroIntervention. 2017 Jun 20;13(3):294-302. doi: 10.4244/EIJ-D-16-00787.
7
Optical Coherence Tomography to Optimize Results of Percutaneous Coronary Intervention in Patients with Non-ST-Elevation Acute Coronary Syndrome: Results of the Multicenter, Randomized DOCTORS Study (Does Optical Coherence Tomography Optimize Results of Stenting).光学相干断层成像术优化非 ST 段抬高型急性冠状动脉综合征患者经皮冠状动脉介入治疗的结果:多中心、随机 DOCTORS 研究的结果(光学相干断层成像术是否优化支架置入术的结果)。
Circulation. 2016 Sep 27;134(13):906-17. doi: 10.1161/CIRCULATIONAHA.116.024393. Epub 2016 Aug 29.
8
Fully Convolutional Networks for Semantic Segmentation.全卷积网络用于语义分割。
IEEE Trans Pattern Anal Mach Intell. 2017 Apr;39(4):640-651. doi: 10.1109/TPAMI.2016.2572683. Epub 2016 May 24.
9
Automated detection of vessel lumen and stent struts in intravascular optical coherence tomography to evaluate stent apposition and neointimal coverage.利用血管内光学相干断层扫描自动检测血管腔和支架支柱,以评估支架贴壁情况和新生内膜覆盖情况。
Med Phys. 2016 Apr;43(4):1662. doi: 10.1118/1.4943374.
10
3-D Stent Detection in Intravascular OCT Using a Bayesian Network and Graph Search.基于贝叶斯网络和图搜索的血管内光学相干断层扫描中三维支架检测
IEEE Trans Med Imaging. 2015 Jul;34(7):1549-1561. doi: 10.1109/TMI.2015.2405341. Epub 2015 Feb 24.

基于深度卷积模型的光学相干断层扫描自动支架重建

Automatic stent reconstruction in optical coherence tomography based on a deep convolutional model.

作者信息

Wu Peng, Gutiérrez-Chico Juan Luis, Tauzin Hélène, Yang Wei, Li Yingguang, Yu Wei, Chu Miao, Guillon Benoît, Bai Jingfeng, Meneveau Nicolas, Wijns William, Tu Shengxian

机构信息

Biomedical Instrument Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, No. 1954 Hua Shan Road, 200030 Shanghai, China.

Department of Interventional Cardiology, Campo de Gibraltar Health Trust, 11207 - Algeciras, Spain.

出版信息

Biomed Opt Express. 2020 May 29;11(6):3374-3394. doi: 10.1364/BOE.390113. eCollection 2020 Jun 1.

DOI:10.1364/BOE.390113
PMID:32637261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7316028/
Abstract

Intravascular optical coherence tomography (IVOCT) can accurately assess stent apposition and expansion, thus enabling the optimisation of a stenting procedure to minimize the risk of device failure. This paper presents a deep convolutional based model for automatic detection and segmentation of stent struts. The input of pseudo-3D images aggregated the information from adjacent frames to refine the probability of strut detection. In addition, multi-scale shortcut connections were implemented to minimize the loss of spatial resolution and refine the segmentation of strut contours. After training, the model was independently tested in 21,363 cross-sectional images from 170 IVOCT image pullbacks. The proposed model obtained excellent segmentation (0.907 Dice and 0.838 Jaccard) and detection metrics (0.943 precision, 0.940 recall and 0.936 F1-score), significantly better than conventional features-based algorithms. This performance was robust and homogenous among IVOCT pullbacks with different sources of acquisition (clinical centres, imaging operators, type of stent, time of acquisition and challenging scenarios). In addition, excellent agreement between the model and a commercialized software was observed in the quantification of clinically relevant parameters. In conclusion, the deep-convolutional model can accurately detect stent struts in IVOCT images, thus enabling the fully-automatic quantification of stent parameters in an extremely short time. It might facilitate the application of quantitative IVOCT analysis in real-world clinical scenarios.

摘要

血管内光学相干断层扫描(IVOCT)可以准确评估支架贴壁和扩张情况,从而优化支架置入手术,将器械故障风险降至最低。本文提出了一种基于深度卷积的模型,用于自动检测和分割支架支柱。伪3D图像的输入聚合了相邻帧的信息,以提高支柱检测的概率。此外,还采用了多尺度捷径连接,以尽量减少空间分辨率的损失,并细化支柱轮廓的分割。训练后,该模型在来自170次IVOCT图像回撤的21363张横截面图像上进行了独立测试。所提出的模型获得了出色的分割结果(Dice系数为0.907,Jaccard系数为0.838)和检测指标(精确率为0.943,召回率为0.940,F1分数为0.936),明显优于传统的基于特征的算法。在不同采集来源(临床中心、成像操作人员、支架类型、采集时间和具有挑战性的场景)的IVOCT回撤中,这种性能具有稳健性和同质性。此外,在临床相关参数的量化方面,该模型与一款商业化软件之间观察到了出色的一致性。总之,深度卷积模型可以准确检测IVOCT图像中的支架支柱,从而在极短时间内实现支架参数的全自动量化。它可能会促进定量IVOCT分析在实际临床场景中的应用。