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Predicting longevity responses to dietary restriction: A stepping stone toward precision geroscience.

作者信息

Perez-Matos Maria C, Mair William B

机构信息

Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America.

出版信息

PLoS Genet. 2020 Jul 9;16(7):e1008833. doi: 10.1371/journal.pgen.1008833. eCollection 2020 Jul.

DOI:10.1371/journal.pgen.1008833
PMID:32644994
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7347097/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/190d/7347097/3d953fb823c0/pgen.1008833.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/190d/7347097/3d953fb823c0/pgen.1008833.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/190d/7347097/3d953fb823c0/pgen.1008833.g001.jpg

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本文引用的文献

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PLoS Genet. 2020 Jul 9;16(7):e1008835. doi: 10.1371/journal.pgen.1008835. eCollection 2020 Jul.
2
Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice.饮食限制后重组近交系小鼠中硫化氢信号网络的菌株特异性。
Geroscience. 2020 Apr;42(2):801-812. doi: 10.1007/s11357-020-00168-2. Epub 2020 Mar 11.
3
Identification and Application of Gene Expression Signatures Associated with Lifespan Extension.
Geriatrics (Basel). 2020 Nov 19;5(4):95. doi: 10.3390/geriatrics5040095.
4
The relationship between longevity and diet is genotype dependent and sensitive to desiccation in .长寿和饮食之间的关系是由基因型决定的，并对 的干燥敏感。
J Exp Biol. 2020 Dec 2;223(Pt 23):jeb230185. doi: 10.1242/jeb.230185.
鉴定和应用与寿命延长相关的基因表达特征。
Cell Metab. 2019 Sep 3;30(3):573-593.e8. doi: 10.1016/j.cmet.2019.06.018. Epub 2019 Jul 25.
4
Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness.基因型到表型：饮食与线粒体 DNA 单倍型相互作用驱动代谢灵活性和生物适应性。
PLoS Genet. 2018 Nov 6;14(11):e1007735. doi: 10.1371/journal.pgen.1007735. eCollection 2018 Nov.
5
Natural genetic variation in identified genomic loci controlling metabolite levels.鉴定出控制代谢物水平的基因组位点的自然遗传变异。
Genome Res. 2018 Sep;28(9):1296-1308. doi: 10.1101/gr.232322.117. Epub 2018 Aug 14.
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Genetic Dissection of Nutrition-Induced Plasticity in Insulin/Insulin-Like Growth Factor Signaling and Median Life Span in a Multiparent Population.多亲群体中营养诱导的胰岛素/胰岛素样生长因子信号通路可塑性及中位寿命的遗传剖析
Genetics. 2017 Jun;206(2):587-602. doi: 10.1534/genetics.116.197780.
7
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BMC Genomics. 2016 Nov 4;17(1):867. doi: 10.1186/s12864-016-3137-9.
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Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.性别、品系和能量摄入对小鼠衰老特征的影响。
Cell Metab. 2016 Jun 14;23(6):1093-1112. doi: 10.1016/j.cmet.2016.05.027.
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