预测饮食限制对寿命的影响：迈向精准老年科学的垫脚石。 - Suppr

Predicting longevity responses to dietary restriction: A stepping stone toward precision geroscience.

作者信息

Perez-Matos Maria C, Mair William B

机构信息

Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America.

出版信息

PLoS Genet. 2020 Jul 9;16(7):e1008833. doi: 10.1371/journal.pgen.1008833. eCollection 2020 Jul.

DOI:10.1371/journal.pgen.1008833

PMID:32644994

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7347097/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/190d/7347097/3d953fb823c0/pgen.1008833.g001.jpg

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Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice.饮食限制后重组近交系小鼠中硫化氢信号网络的菌株特异性。

Geroscience. 2020 Apr;42(2):801-812. doi: 10.1007/s11357-020-00168-2. Epub 2020 Mar 11.

Identification and Application of Gene Expression Signatures Associated with Lifespan Extension.鉴定和应用与寿命延长相关的基因表达特征。

Cell Metab. 2019 Sep 3;30(3):573-593.e8. doi: 10.1016/j.cmet.2019.06.018. Epub 2019 Jul 25.

Genotype to phenotype: Diet-by-mitochondrial DNA haplotype interactions drive metabolic flexibility and organismal fitness.基因型到表型：饮食与线粒体 DNA 单倍型相互作用驱动代谢灵活性和生物适应性。

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Natural genetic variation in identified genomic loci controlling metabolite levels.鉴定出控制代谢物水平的基因组位点的自然遗传变异。

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Genetics. 2017 Jun;206(2):587-602. doi: 10.1534/genetics.116.197780.

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Predicting longevity responses to dietary restriction: A stepping stone toward precision geroscience.

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