Martín V, Fernández-Villa T, Lamuedra Gil de Gomez M, Mencía-Ares O, Rivero Rodríguez A, Reguero Celada S, Montoro Gómez M, Nuevo Guisado M T, Villa Aller C, Díez Flecha C, Carvajal A, Fernández Vázquez J P
Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS)/Instituto de Biomedicina (IBIOMED), Universidad de León, León, Spain; Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública, CIBERESP, Spain.
Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS)/Instituto de Biomedicina (IBIOMED), Universidad de León, León, Spain.
Semergen. 2020 Aug;46 Suppl 1:35-39. doi: 10.1016/j.semerg.2020.05.014. Epub 2020 Jun 6.
To evaluate the prevalence of and factors associated with SARS-CoV-2 infection in general practitioners and nurses from primary care centers and nursing homes in the Healthcare Area of León (Spain).
Cross-sectional study in a convenience sample of professionals from 30 health centers and 30 nursing homes from the primary care management division of the Healthcare Area of Leon. The work center, type of profession, COVID-19 infection, level of exposure, compliance with preventive measures, isolation (if required) and diagnostic tests carried out were collected. The determination of infection was made by differentiated rapid diagnostic test (dRDT), using a finger-stick whole-blood sample. The association of variables with infection was assessed by multivariable non-conditional logistic regression. The true prevalence of SARS-CoV-2 infection was calculated according to two scenarios for RDT (Sensitivity=0.6 and Specificity=0.985; Sensitivity=0.8 and Specificity=1).
The true prevalence of SARS-CoV-2 infection was between 4.9% and 11.0%. The observed prevalence was 5.9% and was higher in nursing homes than in primary care centers (9.5% vs. 5.5%). No statistically significant differences were observed by sex, type of professional, level of exposure or compliance with preventive measures.
The prevalence of SARS-CoV-2 infection in this group is low. A high number of professionals remain susceptible to SARS-CoV-2 infection and therefore protective measures should be taken, especially for professionals working in nursing homes.
评估西班牙莱昂医疗区基层医疗中心和养老院的全科医生及护士中新型冠状病毒2(SARS-CoV-2)感染的患病率及相关因素。
对莱昂医疗区基层医疗管理部门下属30个健康中心和30个养老院的专业人员进行便利抽样横断面研究。收集工作中心、职业类型、新冠病毒疾病(COVID-19)感染情况、暴露水平、预防措施依从性、隔离情况(如有要求)以及所进行的诊断检测。采用手指采血全血样本,通过差异化快速诊断检测(dRDT)确定感染情况。通过多变量非条件逻辑回归评估变量与感染之间的关联。根据两种检测情况(灵敏度=0.6,特异度=0.985;灵敏度=0.8,特异度=1)计算SARS-CoV-2感染的真实患病率。
SARS-CoV-2感染的真实患病率在4.9%至11.0%之间。观察到的患病率为5.9%,养老院中的患病率高于基层医疗中心(9.5%对5.5%)。在性别、职业类型、暴露水平或预防措施依从性方面未观察到统计学上的显著差异。
该群体中SARS-CoV-2感染的患病率较低。大量专业人员仍易感染SARS-CoV-2,因此应采取保护措施,尤其是针对在养老院工作的专业人员。