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Safety at the Time of the COVID-19 Pandemic: How to Keep our Oncology Patients and Healthcare Workers Safe.2019年冠状病毒病大流行期间的安全:如何保障我们的肿瘤患者和医护人员的安全。
J Natl Compr Canc Netw. 2020 Apr 15:1-6. doi: 10.6004/jnccn.2020.7572.
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Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China.新型冠状病毒肺炎(SARS-CoV-2)感染的癌症患者:一项中国全国性分析。
Lancet Oncol. 2020 Mar;21(3):335-337. doi: 10.1016/S1470-2045(20)30096-6. Epub 2020 Feb 14.
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Consistent Detection of 2019 Novel Coronavirus in Saliva.唾液中 2019 新型冠状病毒的持续检测。
Clin Infect Dis. 2020 Jul 28;71(15):841-843. doi: 10.1093/cid/ciaa149.
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Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28 January 2020.2020 年 1 月 20 日至 28 日,中国武汉旅行者感染 2019 年新型冠状病毒(2019-nCoV)的潜伏期。
Euro Surveill. 2020 Feb;25(5). doi: 10.2807/1560-7917.ES.2020.25.5.2000062.
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A new coronavirus associated with human respiratory disease in China.一种在中国与人类呼吸道疾病相关的新型冠状病毒。
Nature. 2020 Mar;579(7798):265-269. doi: 10.1038/s41586-020-2008-3. Epub 2020 Feb 3.
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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.新型冠状病毒感染肺炎在中国武汉的早期传播动力学。
N Engl J Med. 2020 Mar 26;382(13):1199-1207. doi: 10.1056/NEJMoa2001316. Epub 2020 Jan 29.
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A Novel Coronavirus from Patients with Pneumonia in China, 2019.2019 年中国肺炎患者中的一种新型冠状病毒。
N Engl J Med. 2020 Feb 20;382(8):727-733. doi: 10.1056/NEJMoa2001017. Epub 2020 Jan 24.
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Evaluation of low-dose thalidomide as induction and maintenance therapy in patients with multiple myeloma not eligible for stem cell transplantation.低剂量沙利度胺作为不适合干细胞移植的多发性骨髓瘤患者诱导和维持治疗的评估。
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Induction, consolidation, and maintenance therapies with arsenic as a single agent for acute promyelocytic leukaemia in a 11-year follow-up.单药砷剂用于急性早幼粒细胞白血病的诱导、巩固及维持治疗:11年随访研究
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2020 年大流行期间,90 天内 279 名癌症患者的 COVID-19 感染评估。

Evaluation of COVID 19 infection in 279 cancer patients treated during a 90-day period in 2020 pandemic.

机构信息

Medical oncologist-Hematologist, Internal Medicine Department, Talaghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Int J Clin Oncol. 2020 Sep;25(9):1581-1586. doi: 10.1007/s10147-020-01734-6. Epub 2020 Jul 11.

DOI:10.1007/s10147-020-01734-6
PMID:32654049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7353830/
Abstract

BACKGROUND

The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period.

METHODS

Cancer patient who required treatment, were evaluated for potential COVID-19 infection in a 90-day period, starting from beginning of this epidemic in Iran, January, to April 19, 2020. For treatment of solid tumor patients, if they did not have symptoms related to COVID-19, just chest X-ray was requested. If they showed COVID-19 related symptoms, high resolution CT scan of lungs was requested. For hematology cancer patients, PCR test for COVID-19 infection was requested as well. Protection measures were considered for personnel of oncology wards.

RESULTS

279 Patients were followed up in this 90-day period. No COVID-19 infection was observed in 92 cases of breast cancer, 14 cases of gastric cancer and 12 cases of pancreaticobiliary cancer. However, in 72 cases of colon cancer, 11 cases of lung cancer, 5 cases brain tumors and 12 cases ovarian cancer; 4 cases of COVID-19 were observed. In the hematology cancers group, which included 14 cases of Hodgkin's disease, 23 cases of lymphoproliferative disorder, 12 cases of acute leukemia and 12 cases of multiple myeloma; 3 cases of COVID-19 were observed.

CONCLUSION

Patients with cancer who need treatment can be treated by taking some measures. These measures include observing individual and collective protection principles in patients and health-care personnel, increasing patients' awareness particularly about self-care behavior, performing a COVID-19 test, and taking a chest X-ray, before the treatment starts.

摘要

背景

本研究旨在调查在伊朗 COVID-19 疫情期间,90 天内需要治疗的癌症患者的 COVID-19 疾病及其结局。

方法

从伊朗 COVID-19 疫情开始的 2020 年 1 月至 4 月 19 日的 90 天内,评估需要治疗的癌症患者是否存在 COVID-19 感染的潜在风险。对于实体瘤患者,如果没有与 COVID-19 相关的症状,仅要求进行胸部 X 光检查。如果出现 COVID-19 相关症状,则要求进行肺部高分辨率 CT 扫描。对于血液系统癌症患者,也要求进行 COVID-19 感染的 PCR 检测。考虑了肿瘤病房工作人员的防护措施。

结果

在这 90 天的随访期间,共 279 例患者。在 92 例乳腺癌、14 例胃癌和 12 例胰胆肿瘤患者中未观察到 COVID-19 感染,但在 72 例结肠癌、11 例肺癌、5 例脑肿瘤和 12 例卵巢癌患者中观察到 4 例 COVID-19 感染。在包括 14 例霍奇金病、23 例淋巴增生性疾病、12 例急性白血病和 12 例多发性骨髓瘤的血液系统癌症组中,观察到 3 例 COVID-19 感染。

结论

需要治疗的癌症患者可以通过采取一些措施进行治疗。这些措施包括在患者和医护人员中遵守个人和集体防护原则,提高患者的意识,特别是关于自我保健行为,在治疗开始前进行 COVID-19 检测、胸部 X 光检查。