Food Safety Science Directorate, Canadian Food Inspection Agency, Ottawa, Canada.
Centre for Foodborne, Environmental and Zoonotic Infectious Diseases, Public Health Agency of Canada, Guelph, Canada.
Foodborne Pathog Dis. 2020 Nov;17(11):672-678. doi: 10.1089/fpd.2019.2776. Epub 2020 May 17.
Antimicrobial resistance (AMR) is a global public health threat. The main purpose of this study was to evaluate AMR in generic and recovered from broiler chickens in Canada. To do this, an analysis of the antimicrobial susceptibility results was performed on a sample of generic and isolates from the 2012 to 2013 national microbiological baseline study in broiler chicken. Of the 1135 generic isolates tested, 940 (82.8%) were resistant to at least one antimicrobial, with a large number of unique AMR profiles observed. Of the 1495 isolates tested, 879 (58.8%) were resistant to at least one antimicrobial. Resistance was most common to aminoglycosides, β-lactams, and tetracyclines and, for generic isolates only, folate inhibitors. Differences in AMR patterns were observed across regions for both and . For , the levels of resistance were similar across the different sectors sampled along the food chain (e.g., slaughterhouse and retail) and the types of product sampled. There were also considerable differences in the levels and patterns of resistance among different serovars, with most Enteritidis isolates being susceptible to all antimicrobials tested.
抗微生物药物耐药性（AMR）是一个全球性的公共卫生威胁。本研究的主要目的是评估加拿大商业肉鸡中分离的 和 对抗微生物药物的耐药性。为此，对 2012 至 2013 年全国肉鸡微生物学基线研究中分离的商业 和 分离株的抗微生物药物敏感性结果进行了分析。在测试的 1135 株 分离株中，有 940 株（82.8%）对至少一种抗微生物药物耐药，观察到大量独特的 AMR 谱。在测试的 1495 株 分离株中，有 879 株（58.8%）对至少一种抗微生物药物耐药。耐药性最常见于氨基糖苷类、β-内酰胺类和四环素类，仅对 分离株而言，还包括叶酸抑制剂。 和 分离株的 AMR 模式在不同地区存在差异。对于 ，在食物链的不同采样点（如屠宰场和零售店）以及采样的产品类型中，耐药水平相似。不同 血清型之间的耐药水平和模式也存在很大差异，大多数 肠炎沙门氏菌分离株对所有测试的抗微生物药物均敏感。
