Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Public Health Nutr. 2020 Dec;23(18):3295-3303. doi: 10.1017/S1368980020001627. Epub 2020 Jul 23.
To evaluate the validity and reproducibility of a 152-item semi-quantitative FFQ (SFFQ) for estimating flavonoid intakes.
Over a 1-year period, participants completed two SFFQ and two weighed 7-d dietary records (7DDR). Flavonoid intakes from the SFFQ were estimated separately using Harvard (SFFQHarvard) and Phenol-Explorer (SFFQPE) food composition databases. 7DDR flavonoid intakes were derived using the Phenol-Explorer database (7DDRPE). Validity was assessed using Spearman's rank correlation coefficients deattenuated for random measurement error (rs), and reproducibility was assessed using rank intraclass correlation coefficients.
This validation study included primarily participants from two large observational cohort studies.
Six hundred forty-one men and 724 women.
When compared with two 7DDRPE, the validity of total flavonoid intake assessed by SFFQPE was high for both men and women (rs = 0·77 and rs = 0·74, respectively). The rs for flavonoid subclasses ranged from 0·47 for flavones to 0·78 for anthocyanins in men and from 0·46 for flavonols to 0·77 for anthocyanins in women. We observed similarly moderate (0·4-0·7) to high (≥0·7) validity when using SFFQHarvard estimates, except for flavonesHarvard (rs = 0·25 for men and rs = 0·19 for women). The SFFQ demonstrated high reproducibility for total flavonoid and flavonoid subclass intake estimates when using either food composition database. The intraclass correlation coefficients ranged from 0·69 (flavonolsPE) to 0·80 (proanthocyanidinsPE) in men and from 0·67 (flavonolsPE) to 0·77 (flavan-3-ol monomersHarvard) in women.
SFFQ-derived intakes of total flavonoids and flavonoid subclasses (except for flavones) are valid and reproducible for both men and women.
评估一种包含 152 个项目的半定量食物频率问卷（SFFQ）评估黄酮类化合物摄入量的有效性和可重复性。
在 1 年期间，参与者完成了两份 SFFQ 和两份为期 7 天的称重饮食记录（7DDR）。使用哈佛（SFFQHarvard）和 Phenol-Explorer（SFFQPE）食物成分数据库分别估计 SFFQ 中的黄酮类化合物摄入量。使用 Phenol-Explorer 数据库（7DDRPE）从 7DDR 中得出黄酮类化合物摄入量。使用斯皮尔曼等级相关系数评估有效性，该系数经过随机测量误差（rs）的衰减，使用等级内组内相关系数评估重现性。
本验证研究主要包括来自两项大型观察性队列研究的参与者。
641 名男性和 724 名女性。
与两份 7DDRPE 相比，SFFQPE 评估的总黄酮摄入量在男性和女性中均具有较高的有效性（rs 分别为 0.77 和 0.74）。黄酮类化合物亚类的 rs 值范围从男性的黄酮类 0.47 到花青素的 0.78，以及女性的黄酮醇 0.46 到花青素的 0.77。当使用 SFFQHarvard 估计值时，我们观察到类似的中等（0.4-0.7）到高（≥0.7）有效性，除了黄酮类化合物 Harvard（男性 rs = 0.25，女性 rs = 0.19）。当使用任一食物成分数据库时，SFFQ 均显示出总黄酮和黄酮类化合物亚类摄入量估计值的高重现性。男性的组内相关系数范围为 0.69（黄酮醇 PE）至 0.80（原花青素 PE），女性的组内相关系数范围为 0.67（黄酮醇 PE）至 0.77（黄烷-3-醇单体 Harvard）。
SFFQ 得出的总黄酮和黄酮类化合物亚类（除了黄酮类化合物）的摄入量在男性和女性中均具有有效性和重现性。
