西西里（意大利）亚种 (Guss.) Troia & Raimondo：精油的分离及其生物活性评价。
Subsp. (Guss.) Troia & Raimondo from Sicily (Italy): Isolation of Essential Oil and Evaluation of Its Bioactivity.
机构信息
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, ed. 17, I-90128 Palermo, Italy.
Department of Earth and Marine Sciences (DISTeM), University of Palermo, Via Archirafi 26, I-90128 Palermo, Italy.
出版信息
Molecules. 2020 Jul 16;25(14):3249. doi: 10.3390/molecules25143249.
Abstract
(L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area. The object of the present study is Sicilian subsp. (Guss.) Troia & Raimondo, classified as an endemic subspecies. Aerial parts of this plant species were subjected to hydrodistillation to obtain an essential oil. A total of 93 compounds were identified with 2,3,6-trimethyl benzaldehyde (19.0%), spathulenol (9.0%), ()-caryophyllene (5.4%), and caryophyllene oxide (5.4%) as the main components. The biological activities of essential oil were also investigated. This oil showed an interesting antioxidant potential in a 2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) test (IC of 14.05 μg/mL). Additionally, hypoglycemic and antilipidemic effects were evaluated. Lipase enzyme was inhibited with an IC value of 41.99 μg/mL. Obtained data demonstrated that could be considered a promising source of bioactive compounds useful for the treatment and management of obesity.
摘要
(L.) Boiss.（伞形科）是一种分布于巴尔干-第勒尼安地区的物种。本研究的对象是西西里亚种（Guss.）Troia & Raimondo，被归类为特有亚种。该植物物种的地上部分经过水蒸馏以获得精油。共鉴定出 93 种化合物，其中 2,3,6-三甲基苯甲醛（19.0%）、斯巴醇（9.0%）、（）-石竹烯（5.4%）和石竹烯氧化物（5.4%）为主要成分。还研究了精油的生物活性。该油在 2,2'-偶氮双（3-乙基苯并噻唑啉-6-磺酸）（ABTS）试验中表现出有趣的抗氧化潜力（IC 为 14.05 μg/mL）。此外，还评估了其降血糖和抗脂质作用。脂肪酶被抑制，IC 值为 41.99 μg/mL。获得的数据表明， 可以被认为是具有生物活性化合物的有前途的来源，这些化合物可用于治疗和管理肥胖症。
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