Taiwan Centers for Disease Control, No. 6, Linsen S. Rd., Jhongjheng District, Taipei, 10050, Taiwan.
College of Medicine, National Taiwan University, No. 1, Sec. 1, Jan-Ai Rd., Taipei, 10617, Taiwan; Expert Advisory Committee of Coronavirus Disease-2019, Taiwan.
J Formos Med Assoc. 2020 Nov;119(11):1601-1607. doi: 10.1016/j.jfma.2020.07.015. Epub 2020 Jul 13.
To describe the epidemiology and outcome of the first 100 COVID-19 cases in Taiwan.
We included the first 100 patients with laboratory-confirmed SARS-CoV-2 infection in Taiwan. Demographic, clinical, epidemiological and laboratory data were extracted from outbreak investigation reports and medical records.
Illness onset of the 100 patients was during January 11 to March 16, 2020. Twenty-nine (29%) had at least one underlying condition and ten (10%) were asymptomatic. Seventy-one were imported, including four clusters. Twenty-nine were locally-acquired, including four clusters. The median days from onset to report was longer in locally-acquired cases (10 vs 3 days). Three patients died (case fatality rate 3%) and all of them had underlying conditions. As of May 13, 2020, 93 had been discharged in stable condition; the median hospital stay was 30 days (range, 10-79 days).
The first 100 cases of COVID-19 in Taiwan showed the persistent threat of imported cases from different countries. Even though sporadic locally-acquired disease has been identified, through contact investigation, isolation, quarantine and implementation of social distancing measures, the epidemic is contained to a manageable level with minimal local transmission.
描述台湾首例 100 例 COVID-19 病例的流行病学和结局。
我们纳入了台湾首例经实验室确诊的 SARS-CoV-2 感染的 100 例患者。从暴发调查报告和病历中提取了人口统计学、临床、流行病学和实验室数据。
100 例患者的发病日期为 2020 年 1 月 11 日至 3 月 16 日。29 例（29%）至少有一个基础疾病，10 例（10%）为无症状感染者。71 例为输入性病例，包括 4 个聚集性病例。29 例为本地感染病例，包括 4 个聚集性病例。本地感染病例的发病至报告中位天数较长（10 天 vs 3 天）。3 例患者死亡（病死率 3%），且均有基础疾病。截至 2020 年 5 月 13 日，93 例患者已出院，病情稳定；中位住院时间为 30 天（范围，10-79 天）。
台湾首例 100 例 COVID-19 病例表明，来自不同国家的输入性病例持续构成威胁。尽管已发现散发性本地传播疾病，但通过接触者调查、隔离、检疫和实施社会疏远措施，疫情得到控制，传播程度较低，处于可管理水平。
