McClements David Julian
Department of Food Science, University of Massachusetts, Amherst, MA 01003, USA; Department of Food Science & Bioengineering, Zhejiang Gongshang University, 18 Xuezheng Street, Zhejiang, Hangzhou 310018, China.
Adv Colloid Interface Sci. 2020 Aug;282:102211. doi: 10.1016/j.cis.2020.102211. Epub 2020 Jul 16.
There is growing interest in the production of foods and beverages with nutrient and nutraceutical profiles tailored to an individual's specific nutritional requirements. In principle, these personalized nutrition products are formulated based on the genetics, epigenetics, metabolism, microbiome, phenotype, lifestyle, age, gender, and health status of a person. A challenge in this area is to create customized functional food and beverage products that contain the required combination of bioactive agents, such as lipids, proteins, carbohydrates, vitamins, minerals, nutraceuticals, prebiotics and probiotics. Nanotechnology may facilitate the development of these kind of products since it can be used to encapsulate one or more bioactive agent in a single colloidal delivery system. This delivery system may contain one or more different kinds of colloidal particle, specifically designed to protect each nutrient in the food, but then deliver it in a bioavailable form after ingestion. This review article provides an overview of the different kinds of bioactives that need to be delivered, as well as some of the challenges associated with incorporating them into functional foods and beverages. It then highlights how nanotech-enabled colloidal delivery systems can be developed to encapsulate multiple bioactive agents in a form suitable for functional food applications, particularly in the personalized nutrition field.
人们对生产营养和营养保健品成分符合个人特定营养需求的食品和饮料的兴趣与日俱增。原则上，这些个性化营养产品是根据个人的基因、表观遗传学、新陈代谢、微生物群、表型、生活方式、年龄、性别和健康状况来配制的。该领域的一个挑战是制造定制的功能性食品和饮料产品，使其包含生物活性剂（如脂质、蛋白质、碳水化合物、维生素、矿物质、营养保健品、益生元和益生菌）所需的组合。纳米技术可能有助于这类产品的开发，因为它可用于在单一胶体递送系统中封装一种或多种生物活性剂。这种递送系统可能包含一种或多种不同类型的胶体颗粒，专门设计用于保护食品中的每种营养素，但在摄入后以生物可利用的形式释放它。这篇综述文章概述了需要递送的不同种类生物活性物质，以及将它们纳入功能性食品和饮料所面临的一些挑战。然后强调了如何开发基于纳米技术的胶体递送系统，以适合功能性食品应用的形式封装多种生物活性剂，特别是在个性化营养领域。
