SARS-CoV-2 receptor ACE2 protein expression in serum is significantly associated with age.
作者信息
Pavel Ana B, Wu Jianni, Renert-Yuval Yael, Del Duca Ester, Glickman Jacob W, Miller Rachel L, Paller Amy S, Krueger James G, Guttman-Yassky Emma
机构信息
Laboratory of Inflammatory Skin Diseases, Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Department of Biomedical Engineering, University of Mississippi, Oxford, MS, USA.
出版信息
Allergy. 2021 Mar;76(3):875-878. doi: 10.1111/all.14522. Epub 2020 Aug 24.
Abstract
摘要
相似文献
1
SARS-CoV-2 receptor ACE2 protein expression in serum is significantly associated with age.血清中SARS-CoV-2受体ACE2蛋白表达与年龄显著相关。
Allergy. 2021 Mar;76(3):875-878. doi: 10.1111/all.14522. Epub 2020 Aug 24.
2
ACE2: The Major Cell Entry Receptor for SARS-CoV-2.血管紧张素转化酶 2：SARS-CoV-2 的主要细胞进入受体。
Lung. 2020 Dec;198(6):867-877. doi: 10.1007/s00408-020-00408-4. Epub 2020 Nov 10.
3
Serum ACE2, Angiotensin II, and Aldosterone Levels Are Unchanged in Patients With COVID-19.血清 ACE2、血管紧张素 II 和醛固酮水平在 COVID-19 患者中保持不变。
Am J Hypertens. 2021 Apr 2;34(3):278-281. doi: 10.1093/ajh/hpaa169.
4
The key role of the level of ACE2 gene expression in SARS-CoV-2 infection.ACE2 基因表达水平在 SARS-CoV-2 感染中的关键作用。
Aging (Albany NY). 2021 Jun 11;13(11):14552-14556. doi: 10.18632/aging.203181.
5
Clinical analysis and pluripotent stem cells-based model reveal possible impacts of ACE2 and lung progenitor cells on infants vulnerable to COVID-19.临床分析和多能干细胞模型揭示 ACE2 和肺祖细胞对易感染 COVID-19 的婴儿可能产生的影响。
Theranostics. 2021 Jan 1;11(5):2170-2181. doi: 10.7150/thno.53136. eCollection 2021.
6
Low plasma angiotensin-converting enzyme 2 level in diabetics increases the risk of severe COVID-19 infection.糖尿病患者血浆血管紧张素转换酶 2 水平低会增加重症 COVID-19 感染的风险。
Aging (Albany NY). 2021 May 6;13(9):12301-12307. doi: 10.18632/aging.202967.
7
Sex differences in COVID-19: candidate pathways, genetics of ACE2, and sex hormones.COVID-19 中的性别差异：候选途径、ACE2 的遗传学和性激素。
Am J Physiol Heart Circ Physiol. 2021 Jan 1;320(1):H296-H304. doi: 10.1152/ajpheart.00755.2020. Epub 2020 Dec 4.
8
Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections.吸烟人群和 COPD 患者小气道中内吞作用机制和 ACE2 的失调会增加其对 SARS-CoV-2（COVID-19）感染的易感性。
Am J Physiol Lung Cell Mol Physiol. 2021 Jan 1;320(1):L158-L163. doi: 10.1152/ajplung.00437.2020. Epub 2020 Nov 11.
9
Genomic, epigenomic, and immune subtype analysis of CTSL/B and SARS-CoV-2 receptor ACE2 in pan-cancer.全癌中CTSL/B和SARS-CoV-2受体ACE2的基因组、表观基因组和免疫亚型分析
Aging (Albany NY). 2020 Nov 20;12(22):22370-22389. doi: 10.18632/aging.104147.
10
Angiotensin-converting enzyme 2: A protective factor in regulating disease virulence of SARS-COV-2.血管紧张素转化酶 2：调节 SARS-CoV-2 疾病毒力的保护因素。
IUBMB Life. 2020 Dec;72(12):2533-2545. doi: 10.1002/iub.2391. Epub 2020 Oct 8.
引用本文的文献
1
Clinical characteristics and risk factors of severe COVID-19 in hospitalized neonates with omicron variant infection: a retrospective study.奥密克戎变异株感染住院新生儿重症 COVID-19 的临床特征和危险因素：一项回顾性研究。
Ital J Pediatr. 2024 Sep 16;50(1):176. doi: 10.1186/s13052-024-01751-5.
2
The weekly P25 of the age of the influenza-like illness shows a higher correlation with COVID-19 mortality than rapid tests and could predict the evolution of COVID-19 pandemics in sentinel surveillance, Piura, Perú, 2021.流感样疾病每周发病率 P25 与 COVID-19 死亡率的相关性高于快速检测，可预测秘鲁皮乌拉哨点监测中 COVID-19 大流行的演变。
PLoS One. 2024 Mar 7;19(3):e0295309. doi: 10.1371/journal.pone.0295309. eCollection 2024.
3
[Clinical characteristics of neonates infected with the Omicron variant of SARS-CoV-2: a multicenter cross-sectional survey].[新型冠状病毒奥密克戎变异株感染新生儿的临床特征：一项多中心横断面调查]
Zhongguo Dang Dai Er Ke Za Zhi. 2023 Jul 15;25(7):678-684. doi: 10.7499/j.issn.1008-8830.2302049.
4
Diversity of immune responses in children highly exposed to SARS-CoV-2.儿童对 SARS-CoV-2 高度暴露后的免疫反应多样性。
Front Immunol. 2023 Mar 3;14:1105237. doi: 10.3389/fimmu.2023.1105237. eCollection 2023.
5
Proteomic characterization of atopic dermatitis blood from infancy to adulthood.从婴儿期到成年期特应性皮炎血液的蛋白质组学特征。
J Am Acad Dermatol. 2023 May;88(5):1083-1093. doi: 10.1016/j.jaad.2022.12.050. Epub 2023 Feb 10.
6
Concentrations of Soluble Angiotensin Converting Enzyme 2 (sACE2) in Children and Adults with and without COVID-19.患有和未患有新冠肺炎的儿童及成人中可溶性血管紧张素转换酶2（sACE2）的浓度
J Clin Med. 2022 Nov 17;11(22):6799. doi: 10.3390/jcm11226799.
7
Age-related differences in SARS-CoV-2 binding factors: An explanation for reduced susceptibility to severe COVID-19 among children?年龄相关的 SARS-CoV-2 结合因子差异：儿童对严重 COVID-19 易感性降低的解释？
Paediatr Respir Rev. 2022 Dec;44:61-69. doi: 10.1016/j.prrv.2022.01.008. Epub 2022 Feb 8.
8
Soluble ACE2 and TMPRSS2 Levels in the Serum of Asthmatic Patients.哮喘患者血清中可溶性 ACE2 和 TMPRSS2 水平。
J Korean Med Sci. 2022 Feb 28;37(8):e65. doi: 10.3346/jkms.2022.37.e65.
9
Characterization of the antibody response to SARS-CoV-2 in a mildly affected pediatric population.描述轻症儿童群体对 SARS-CoV-2 的抗体反应。
Pediatr Allergy Immunol. 2022 Feb;33(2):e13737. doi: 10.1111/pai.13737.
10
Multiplex Antibody Analysis of IgM, IgA and IgG to SARS-CoV-2 in Saliva and Serum From Infected Children and Their Close Contacts.对感染儿童及其密切接触者唾液和血清中针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的IgM、IgA和IgG进行多重抗体分析。
Front Immunol. 2022 Jan 27;13:751705. doi: 10.3389/fimmu.2022.751705. eCollection 2022.
本文引用的文献
1
Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors.在健康人群以及哮喘、COPD、肥胖、高血压和 COVID-19 危险因素患者的组织和免疫细胞中，ACE2、CD147、CD26 和其他 SARS-CoV-2 相关分子的分布。
Allergy. 2020 Nov;75(11):2829-2845. doi: 10.1111/all.14429. Epub 2020 Aug 24.
2
Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults.儿童和成人鼻内血管紧张素转换酶 2 的基因表达。
JAMA. 2020 Jun 16;323(23):2427-2429. doi: 10.1001/jama.2020.8707.
3
Age and sex differences in soluble ACE2 may give insights for COVID-19.可溶性血管紧张素转换酶2的年龄和性别差异可能为新冠病毒疾病提供见解。
Crit Care. 2020 May 14;24(1):221. doi: 10.1186/s13054-020-02942-2.
4
Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues.SARS-CoV-2 细胞受体基因 ACE2 在多种人类组织中的表达。
Infect Dis Poverty. 2020 Apr 28;9(1):45. doi: 10.1186/s40249-020-00662-x.
5
Coronavirus Disease 2019 in Children - United States, February 12-April 2, 2020.2019 年冠状病毒病在儿童中的情况-美国，2020 年 2 月 12 日至 4 月 2 日。
MMWR Morb Mortal Wkly Rep. 2020 Apr 10;69(14):422-426. doi: 10.15585/mmwr.mm6914e4.
6
Epidemiology of COVID-19 Among Children in China.中国儿童 COVID-19 流行病学。
Pediatrics. 2020 Jun;145(6). doi: 10.1542/peds.2020-0702. Epub 2020 Mar 16.
7
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.中国武汉成人 COVID-19 住院患者的临床病程和死亡危险因素：一项回顾性队列研究。
Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11.
8
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）进入细胞依赖于 ACE2 和 TMPRSS2，可被一种临床验证的蛋白酶抑制剂所阻断。
Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052. Epub 2020 Mar 5.
9
The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease.早期发病的儿童特应性皮炎的血液蛋白质组学特征显示全身性炎症，与成人长期疾病不同。
J Am Acad Dermatol. 2019 Aug;81(2):510-519. doi: 10.1016/j.jaad.2019.04.036. Epub 2019 Apr 19.
10
Cathepsin L functionally cleaves the severe acute respiratory syndrome coronavirus class I fusion protein upstream of rather than adjacent to the fusion peptide.组织蛋白酶L对严重急性呼吸综合征冠状病毒I类融合蛋白进行功能性切割的位置是在融合肽上游而非与其相邻处。
J Virol. 2008 Sep;82(17):8887-90. doi: 10.1128/JVI.00415-08. Epub 2008 Jun 18.
Zotero 插件