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实施全国性社会隔离政策与 COVID19 感染率的急剧下降相对应。

Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates.

机构信息

Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.

Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.

出版信息

PLoS One. 2020 Jul 30;15(7):e0236619. doi: 10.1371/journal.pone.0236619. eCollection 2020.

Abstract

The outbreak the SARS-CoV-2 (CoV-2) virus has resulted in over 6.5 million cases of COVID19, greatly stressing global healthcare infrastructure. Lacking medical prophylactic measures to combat disease spread, many nations have adopted social distancing policies in order to mitigate transmission of CoV-2. While mathematical models have suggested the efficacy of social distancing to curb the spread of CoV-2, there is a lack of systematic studies to quantify the real-world efficacy of these approaches. Here, we first demonstrate that implementation of social distancing policies in US states corresponded with a reduction in COVID19 spread rates, and that the reduction in spread rate is proportional to the average change in mobility. We validate this observation on a worldwide scale by analyzing COVID19 spread rate in 134 nations with varying social distancing policies. Globally, we find that social distancing policies significantly reduced the COVID19 spread rate, with resulting in an estimated 65% reduction (95% CI = 39-80%) in new COVID19 cases over a two week time period. These data suggest that social distancing policies may be a powerful tool to prevent spread of COVID19 in real-world scenarios.

摘要

SARS-CoV-2(CoV-2)病毒的爆发导致了超过 650 万例 COVID19 病例,极大地加剧了全球医疗基础设施的压力。由于缺乏预防疾病传播的医疗措施,许多国家都采取了社会隔离政策,以减轻 CoV-2 的传播。虽然数学模型表明社会隔离措施对遏制 CoV-2 的传播是有效的,但缺乏系统的研究来量化这些方法的实际效果。在这里,我们首先证明美国各州实施社会隔离政策与 COVID19 传播率的降低有关,而且传播率的降低与流动性的平均变化成正比。我们通过分析 134 个采取不同社会隔离政策的国家的 COVID19 传播率,在全球范围内验证了这一观察结果。全球范围内,我们发现社会隔离政策显著降低了 COVID19 的传播率,在两周的时间内估计使新的 COVID19 病例减少了 65%(95%置信区间为 39-80%)。这些数据表明,社会隔离政策可能是预防 COVID19 在现实场景中传播的有力工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/654a/7392246/6c7ab9c01609/pone.0236619.g001.jpg

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