Bhuiyan Md Shakhawat Hossen, Miah Muhammed Yusuf, Paul Shujit Chandra, Aka Tutun Das, Saha Otun, Rahaman Md Mizanur, Sharif Md Jahidul Islam, Habiba Ommay, Ashaduzzaman Md
Department of Applied Chemistry and Chemical Engineering, Noakhali Science and Technology University, Sonapur 3814, Noakhali, Bangladesh.
Department of Pharmacy, Noakhali Science and Technology University, Sonapur 3814, Noakhali, Bangladesh.
Heliyon. 2020 Aug 4;6(8):e04603. doi: 10.1016/j.heliyon.2020.e04603. eCollection 2020 Aug.
Synthesis of iron oxide nanoparticles by the recently developed green approach is extremely promising because of its non-toxicity and environmentally friendly behavior. In this study, nano scaled iron oxide particles (α-FeO) were synthesized from hexahydrate ferric chloride (FeCl.6HO) with the addition of papaya () leaf extract under atmospheric conditions. The synthesis of iron oxide nanoparticles was confirmed by systematic characterization using FTIR, XRD, FESEM, EDX and TGA studies. The removal efficiency of remazol yellow RR dye with the synthesized iron oxide nanoparticles as a photocatalyst was determined along with emphasizing on the parameters of catalyst dosage, initial dye concentration and pH. Increasing the dose of iron oxide nanoparticles enhanced the decolorization of the dyes and a maximum 76.6% dye degradation was occurred at pH 2 after 6 h at a catalyst dose of 0.8 g/L. Unit removal capacity of the photocatalyst was found to be 340 mg/g at dye concentration of 70 ppm and at a catalyst dose of 0.4 g/L. The synthesized nanoparticles showed moderate antibacterial activity against spp. spp. bacterial strains. Although the cytotoxic effect of nanoparticles against Hela, BHK-21 and Vero cell line was found to be toxic at maximum doses but it can be considered for tumor cell damage because it showed excellent activity against the Hela and BHK-21 cell lines.
通过最近开发的绿色方法合成氧化铁纳米颗粒极具前景，因为其具有无毒和环保的特性。在本研究中，在大气条件下，以六水合氯化铁（FeCl₃·6H₂O）为原料，添加木瓜叶提取物，合成了纳米级氧化铁颗粒（α-Fe₂O₃）。通过傅里叶变换红外光谱（FTIR）、X射线衍射（XRD）、场发射扫描电子显微镜（FESEM）、能谱分析（EDX）和热重分析（TGA）等系统表征手段证实了氧化铁纳米颗粒的合成。以合成的氧化铁纳米颗粒作为光催化剂，测定了其对活性艳黄RR染料的去除效率，并着重研究了催化剂用量、初始染料浓度和pH值等参数。增加氧化铁纳米颗粒的用量可提高染料的脱色率，在催化剂用量为0.8 g/L、pH为2的条件下，6小时后染料降解率最高可达76.6%。在染料浓度为70 ppm、催化剂用量为0.4 g/L时，光催化剂的单位去除容量为340 mg/g。合成的纳米颗粒对金黄色葡萄球菌和大肠杆菌等细菌菌株表现出中等抗菌活性。尽管纳米颗粒对Hela、BHK-21和Vero细胞系的细胞毒性在最大剂量时表现为有毒，但由于其对Hela和BHK-21细胞系表现出优异的活性，可考虑用于肿瘤细胞损伤。
