两种快速显微镜检查方法与培养法对患者标本中沙眼衣原体检测的多中心比较评估
Multicenter comparative evaluation of two rapid microscopic methods and culture for detection of Chlamydia trachomatis in patient specimens.
作者信息
Tilton R C, Judson F N, Barnes R C, Gruninger R P, Ryan R W, Steingrimsson O
机构信息
University of Connecticut School of Medicine, Farmington 06032.
出版信息
J Clin Microbiol. 1988 Feb;26(2):167-70. doi: 10.1128/jcm.26.2.167-170.1988.
Abstract
Four hundred and seventy-three men and women at high risk for sexually transmitted disease were tested for the presence of Chlamydia trachomatis in the urethra or the endocervix. Four groups were involved in this multicenter study of two direct fluorescent-antibody microscopy tests, Kallestad Pathfinder and Syva Microtrak, compared with culture techniques. Results from the test sites indicated that there was no significant difference overall in the sensitivity and specificity of the two test kits. However, there was some interlaboratory variation seen in the sensitivity of the microscopy, but little difference in the specificity. Either kit could be an effective screening method for C. trachomatis in high-risk populations.
摘要
对473名性传播疾病高危男女的尿道或宫颈管进行沙眼衣原体检测。本多中心研究涉及四组，将两种直接荧光抗体显微镜检测方法（Kallestad Pathfinder和Syva Microtrak）与培养技术进行比较。检测点的结果表明，两种检测试剂盒的敏感性和特异性总体上没有显著差异。然而，显微镜检测的敏感性在不同实验室之间存在一些差异，但特异性差异不大。两种试剂盒都可以作为高危人群沙眼衣原体的有效筛查方法。
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本文引用的文献
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