Jiang Shengjie, Lin Kaili, Cai Ming
Department of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
National Clinical Research Center for Oral Diseases, Shanghai, China.
Front Chem. 2020 Jul 21;8:580. doi: 10.3389/fchem.2020.00580. eCollection 2020.
The prevalence of various diseases caused by bacteria has been increasing, and some traditional antibiotics have been reported to have varying degrees of resistance. ZnO nanomaterials (ZnO-NMs), due to their excellent broad-spectrum antibacterial properties, lasting antibacterial effects, and excellent biocompatibility, have quickly become the research focus of new antibacterial agents. While the narrow light response range of ZnO-NMs has limited the antibacterial performance to some extent and modifying it by various means to improve its response under visible light, such as doping metal/non-metal atoms, depositing noble metals and coupling carbon materials, which is a new research hotspot. Herein, the current mainstream claims about the antibacterial mechanisms and applications of ZnO-NMs are reviewed.
由细菌引起的各种疾病的患病率一直在上升，并且据报道一些传统抗生素具有不同程度的耐药性。氧化锌纳米材料（ZnO-NMs）由于其优异的广谱抗菌性能、持久的抗菌效果和出色的生物相容性，迅速成为新型抗菌剂的研究热点。虽然ZnO-NMs较窄的光响应范围在一定程度上限制了其抗菌性能，通过各种手段对其进行改性以提高其在可见光下的响应，如掺杂金属/非金属原子、沉积贵金属和耦合碳材料，这是一个新的研究热点。在此，对目前关于ZnO-NMs抗菌机制和应用的主流观点进行综述。
