State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
College of Chemistry and Environmental Science, Hebei University, Baoding, Hebei 071003, China.
Environ Sci Technol. 2020 Sep 15;54(18):11333-11343. doi: 10.1021/acs.est.0c04299. Epub 2020 Sep 1.
Parabens, triclosan (TCS), triclocarban (TCC), and bisphenol A and its analogues (BPs) are used in various industrial and consumer products and are typical endocrine-disrupting chemicals (EDCs). In this study, six parabens, TCS, TCC, and eight BPs were determined in 289 indoor dusts collected from different geographical regions in China. Ten of 16 target compounds were found in >50% samples. Concentrations of Σparabens, Σ(TCS+TCC), and ΣBPs in indoor dust ranged from 8.66-21,500 (median: 288), 19.6-8940 (104), and 8.80-37,400 (377) ng/g dw, respectively. The Σ(TCS+TCC) concentrations in dust from Northeast China were higher than those from Central South China ( < 0.05). The concentrations of ΣBPs in dust from Eastern China were approximately 2 times higher than those found for North China ( < 0.05), whereas there was no significant spatial difference in concentrations of parabens among different geographical regions ( > 0.05). Human exposure to these EDCs through indoor dust ingestion and dermal absorption was evaluated. The median and 95th percentile estimated daily intakes of ΣEDCs ranged from 0.439 (adults)-4.57 (infants) and 6.26 (adults)-62.1 (infants) ng/kg bw/day, respectively, generally decreasing with increasing age. This nationwide survey establishes a baseline concentration for parabens in the indoor environment in China.
防腐剂、三氯生 (TCS)、三氯卡班 (TCC)、双酚 A 及其类似物 (BPs) 广泛应用于各种工业和消费品中，是典型的内分泌干扰化学物质 (EDCs)。本研究测定了中国不同地理区域采集的 289 份室内灰尘中 6 种防腐剂、TCS、TCC 和 8 种 BPs。在 >50%的样本中发现了 16 种目标化合物中的 10 种。室内灰尘中Σ 防腐剂、Σ(TCS+TCC) 和 ΣBPs 的浓度范围分别为 8.66-21,500（中位数：288）、19.6-8940（104）和 8.80-37,400（377）ng/g dw。东北室内灰尘中Σ(TCS+TCC)的浓度高于中南（<0.05）。华东地区室内灰尘中 ΣBPs 的浓度约为华北地区的 2 倍（<0.05），而不同地理区域之间的防腐剂浓度没有明显的空间差异（>0.05）。评估了通过室内灰尘摄入和皮肤吸收接触这些 EDCs 的人体暴露情况。ΣEDCs 的估计日摄入量中值和 95 百分位数范围分别为 0.439（成人）-4.57（婴儿）和 0.626（成人）-62.1（婴儿）ng/kg bw/day，通常随年龄的增长而降低。这项全国性调查为中国室内环境中防腐剂的浓度建立了基线。
