Gelbart S M, Prabhudesai M M
University of Illinois School of Clinical Medicine, Urbana/Champaign.
J Am Geriatr Soc. 1988 Apr;36(4):339-41. doi: 10.1111/j.1532-5415.1988.tb02361.x.
A dipstick method for bacteriologic screening of urine using a combination of leukocyte esterase and nitrite indicators, Chemstrip LN, was evaluated in a male inpatient geriatric population. Three hundred seventy-five urine samples from 198 symptomatic patients (age range, 45 to 98 years; mean, 69.6) were tested by LN and cultured using standard methods. LN showed 169 negatives, but in 7 of these cases, the culture was positive (greater than or equal to 5 X 10(4) col/mL). Organisms recovered from these cultures were Candida (not albicans), Group B Streptococcus, Staphylococcus aureus, and in four cases, Pseudomonas aeruginosa. In the four cases of missed Pseudomonas the patients were receiving aminoglycoside therapy for 2 to 6 days and/or drugs that dye the urine. Despite the fact that many patients were on medications known to interfere with the test strips, the negative predictive value was still 96.0% showing that the strips may be suitable for use with this population given the understanding that certain antibiotics and/or substances that dye the urine may give false negative results.
使用白细胞酯酶和亚硝酸盐指示剂组合的尿液细菌学筛查试纸法（Chemstrip LN）在老年男性住院患者群体中进行了评估。对198例有症状患者（年龄范围45至98岁；平均69.6岁）的375份尿液样本进行了LN检测，并采用标准方法进行培养。LN显示169份为阴性，但其中7例培养结果为阳性（≥5×10⁴菌落/mL）。从这些培养物中分离出的微生物有念珠菌（非白色念珠菌）、B族链球菌、金黄色葡萄球菌，4例为铜绿假单胞菌。在4例漏检铜绿假单胞菌的病例中，患者接受了2至6天的氨基糖苷类治疗和/或服用了使尿液染色的药物。尽管许多患者正在服用已知会干扰试纸条的药物，但阴性预测值仍为96.0%，这表明在了解某些抗生素和/或使尿液染色的物质可能会产生假阴性结果的情况下，试纸条可能适用于该人群。
