Département de Génétique Médicale, unité INSERM U933, Hôpital Armand-Trousseau, Assistance Publique-Hôpitaux de Paris, Paris, France.
Département de Cardiologie, CHU Montpellier, Montpellier, France.
Epidemiol Infect. 2020 Aug 19;148:e184. doi: 10.1017/S0950268820001831.
Purpose: The novel coronavirus (severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)) first appeared in Wuhan, China, in December 2019, and rapidly spread across the globe. Since most respiratory viruses are known to show a seasonal pattern of infection, it has been hypothesised that SARS-CoV-2 may be seasonally dependent as well. The present study looks at a possible effect of atmospheric temperature, which is one of the suspected factors influencing seasonality, on the evolution of the pandemic. Basic procedures: Since confirming a seasonal pattern would take several more months of observation, we conducted an innovative day-to-day micro-correlation analysis of nine outbreak locations, across four continents and both hemispheres, in order to examine a possible relationship between atmospheric temperature (used as a proxy for seasonality) and outbreak progression. Main findings: There was a negative correlation between atmospheric temperature variations and daily new cases growth rates, in all nine outbreaks, with a median lag of 10 days. Principal conclusions: The results presented here suggest that high temperatures might dampen SARS-CoV-2 propagation, while lower temperatures might increase its transmission. Our hypothesis is that this could support a potential effect of atmospheric temperature on coronavirus disease progression, and potentially a seasonal pattern for this virus, with a peak in the cold season and rarer occurrences in the summer. This could guide government policy in both the Northern and Southern hemispheres for the months to come.
新型冠状病毒(严重急性呼吸系统综合症冠状病毒 2 型(SARS-CoV-2))于 2019 年 12 月在中国武汉首次出现,并迅速在全球范围内传播。由于大多数呼吸道病毒的感染呈季节性模式,因此有人假设 SARS-CoV-2 可能也具有季节性依赖性。本研究探讨了大气温度(影响季节性的可疑因素之一)对大流行演变的可能影响。基本程序:由于确认季节性模式还需要几个月的观察,因此我们对来自四大洲和两个半球的九个暴发地点进行了创新的日常微观相关性分析,以检验大气温度(用作季节性的替代物)与暴发进展之间的可能关系。主要发现:在所有九个暴发中,大气温度变化与每日新增病例增长率之间存在负相关关系,中位数滞后 10 天。主要结论:这里呈现的结果表明,高温可能会抑制 SARS-CoV-2 的传播,而低温可能会增加其传播。我们的假设是,这可能支持大气温度对冠状病毒病进展的潜在影响,以及这种病毒的季节性模式,冬季高峰,夏季出现的频率较低。这可以为未来几个月南北半球的政府政策提供指导。