Zhang Han, Chen Guopu, Yu Yunru, Guo Jiahui, Tan Qian, Zhao Yuanjin
Department of Burns and Plastic Surgery Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School Nanjing 210008 P. R. China.
Department of Clinical Laboratory Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical University Nanjing 210008 P. R. China.
Adv Sci (Weinh). 2020 Jun 11;7(16):2000789. doi: 10.1002/advs.202000789. eCollection 2020 Aug.
Surface materials with specific wettability play significant roles in existing fields from environmental protection to biomedicine. Here, a 3D droplet transport microfiber textile with slippery liquid-infused porous surface is presented for medical drainage around wounds. The textile is fabricated by using a simple capillary microfluidic printing method to continuously spin polyurethane microfibers with liquid paraffin-infused porous surface and print them into a 3D-structure. Benefiting from the specific surface porous structure and oil encapsulation of the microfibers, aqueous droplets could be nondestructively and rapidly transported not only in simple single, double or multiple microfiber systems, but also in the microfibers composed stereoscopic textile through the microfluidic 3D printing. Based on this feature, it is demonstrated that the 3D slippery microfiber textile coupled with a vacuum sealing drainage therapy could significantly enhance the wound exudation drainage efficiency, reduce tissue injury, and prolong the effective service life in versatile wounds management. Thus, it is believed that the slippery microfiber textiles have potential for clinical applications.
具有特定润湿性的表面材料在从环境保护到生物医学等现有领域中发挥着重要作用。在此，提出了一种具有注入滑液的多孔表面的3D液滴传输微纤维织物，用于伤口周围的医疗引流。该织物采用简单的毛细管微流控印刷方法制造，以连续纺制具有注入液体石蜡的多孔表面的聚氨酯微纤维，并将它们印刷成3D结构。受益于微纤维的特定表面多孔结构和油封装，水滴不仅可以在简单的单根、双根或多根微纤维系统中无损且快速地传输，还可以通过微流控3D印刷在由立体织物组成的微纤维中传输。基于这一特性，证明了3D滑爽微纤维织物与真空密封引流疗法相结合可以显著提高伤口渗出液的引流效率，减少组织损伤，并在多功能伤口管理中延长有效使用寿命。因此，人们认为滑爽微纤维织物具有临床应用潜力。
