Amesz Stella F, Klein Toni M, Meulendijks Audrey M, Nguyen Tuong-Vi, Blome Christine, Roodbol Petrie F, van Montfrans Catherine
University of Groningen, Faculty of Medical Sciences, Kerkstraat 4, 8162RS, Epe, the Netherlands.
German Centre for Health Services Research in Dermatology (CVderm), Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
BMC Dermatol. 2020 Aug 26;20(1):5. doi: 10.1186/s12895-020-00101-2.
Chronic wounds have a major impact on patients' health-related quality of life (HRQoL). Therefore, measuring HRQoL is an indispensable part of the treatment of patients with chronic wounds. The aim of this study was to translate and validate the Wound-QoL, a wound-specific HRQoL questionnaire, in a Dutch population.
The Wound-QoL was translated into Dutch according to the international standards. Patients with chronic wounds were asked to complete questionnaires at baseline (T0) and after six weeks (T1), including Wound-QoL, EQ-5D-3L (a generic questionnaire to measure HRQoL) and a visual analogue scale (VAS) measuring wound pain. If patients were not able to complete the questionnaire by themselves, it was read out to them by a nurse. Further data were obtained from medical records.
Of the 120 patients included, 64 (53.3%) completed the questionnaire by themselves. To 55 patients (45.8%), the questionnaire was read out. The internal consistency of the Wound-QoL global score was high at both time points (T0: Cronbach's α = 0.89, T1: Cronbach's α = 0.92). The item selectivity for global score ranged from r = 0.25 to r = 0.77 at T0 and from r = 0.40 to r = 0.79 at T1. Overall, the self-completion and read-out subgroups showed similar internal consistency and item selectivity scores. With regard to convergent validity, significant correlations were found between Wound-QoL and EQ-5D-3L (T0: r = - 0.45, p < 0.001, T1: r = - 0.50, p < 0.001) as well as between Wound-QoL and pain VAS (T0: r = 0.23, p = 0.012, T1: r = 0.37, p = 0.001) at both time points. Responsiveness analyses showed significant correlations between changes in Wound-QoL and changes in EQ-5D-3L (r = - 0.37, p < 0.001), pain VAS (r = 0.24, p = 0.044) and wound size (r = 0.24, p = 0.013). The self-completion and read-out subgroups showed differences in convergent validity and responsiveness.
The results indicate that the Dutch version of the Wound-QoL has positive psychometric properties. However, more research is needed to further explore the differences between self-completed and read-out questionnaires.
慢性伤口对患者的健康相关生活质量（HRQoL）有重大影响。因此，测量HRQoL是慢性伤口患者治疗中不可或缺的一部分。本研究的目的是在荷兰人群中翻译并验证一种针对伤口的HRQoL问卷——伤口生活质量问卷（Wound-QoL）。
按照国际标准将Wound-QoL翻译成荷兰语。要求慢性伤口患者在基线时（T0）和六周后（T1）完成问卷，包括Wound-QoL、EQ-5D-3L（一种测量HRQoL的通用问卷）以及一个测量伤口疼痛的视觉模拟量表（VAS）。如果患者无法自行完成问卷，则由护士为其宣读。还从医疗记录中获取了进一步的数据。
纳入的120名患者中，64名（53.3%）自行完成了问卷。55名患者（45.8%）由他人为其宣读问卷。在两个时间点，Wound-QoL总体评分的内部一致性都很高（T0：克朗巴哈系数α = 0.89，T1：克朗巴哈系数α = 0.92）。总体评分的项目选择性在T0时范围为r = 0.25至r = 0.77，在T1时范围为r = 0.40至r = 0.79。总体而言，自行完成问卷组和他人宣读问卷组显示出相似的内部一致性和项目选择性得分。关于收敛效度，在两个时间点均发现Wound-QoL与EQ-5D-3L之间存在显著相关性（T0：r = -0.45, p < 0.001，T1：r = -0.50, p < 0.001），以及Wound-QoL与疼痛VAS之间存在显著相关性（T0：r = 0.23, p = 0.012，T1：r = 0.37, p = 0.001）。反应性分析显示Wound-QoL的变化与EQ-5D-3L的变化（r = -0.37, p < 0.001）、疼痛VAS的变化（r = 0.24, p = 0.044）以及伤口大小的变化（r = 0.24, p = 0.013）之间存在显著相关性。自行完成问卷组和他人宣读问卷组在收敛效度和反应性方面存在差异。
结果表明荷兰版的Wound-QoL具有良好的心理测量学特性。然而，需要更多研究来进一步探讨自行完成问卷和他人宣读问卷之间的差异。
