Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL.
Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL.
J Anim Sci. 2020 Sep 1;98(9). doi: 10.1093/jas/skaa274.
Periodontal disease (PD) is the most common clinical condition occurring in adult dogs. The objective of this study was to evaluate the benefits of daily dental chew administration on oral health outcomes in adult dogs. Twelve adult (mean age = 5.31 ± 1.08 yr; mean BW = 13.12 ± 1.39 kg) female beagle dogs were used in a replicated 4 × 4 Latin square design consisting of 28-d periods. On day 0 of each period, teeth were cleaned by a veterinary dentist blinded to treatments. Teeth then were scored for plaque, calculus, and gingivitis by the same veterinary dentist on day 28 of each period. Breath samples were measured for malodor (volatile sulfur compounds) on days 1, 7, 14, 21, and 27 of each period. All dogs consumed the same commercial dry diet throughout the study. Control dogs were offered the diet only (CT), while treatment groups received the diet plus one of three dental chews. Two novel chews (Bones & Chews Dental Treats [BC]; Chewy, Inc., Dania Beach, FL and Dr. Lyon's Grain-Free Dental Treats [DL]; Dr. Lyon's, LLC, Dania Beach, FL) and a leading brand chew (Greenies Dental Treats [GR]; Mars Petcare US, Franklin, TN) were tested. Each day, one chew was provided 4 h after mealtime. All tooth scoring data were analyzed using the Mixed Models procedure of SAS (version 9.4; SAS Institute, Cary, NC). Halimeter data were analyzed using repeated measures using the Mixed Models procedure of SAS and testing for differences due to treatment, time, and treatment * time interaction. Data are reported as LS means ± SEM with statistical significance set at P < 0.05. DL performed at the same level as the leading brand, GR, as both resulted in lower (P < 0.05) plaque coverage and thickness scores, calculus coverage scores, and day 27 volatile sulfur concentrations compared with CT. Additionally, DL reduced (P < 0.05) volatile sulfur compounds on day 14 when compared with CT. BC reduced (P < 0.05) calculus coverage and day 27 volatile sulfur concentrations compared with CT. Our results suggest that the dental chews tested in this study may help slow the development and/or progression of PD in dogs.
牙周病（PD）是成年犬最常见的临床病症。本研究旨在评估每日咀嚼牙齿护理对成年犬口腔健康的益处。使用 12 只成年（平均年龄=5.31 ± 1.08 岁；平均体重=13.12 ± 1.39kg）雌性比格犬，采用 28 天的 4×4 拉丁方设计。在每个周期的第 0 天，由兽医牙医对牙齿进行清洁，而在每个周期的第 28 天，由同一位兽医牙医对牙齿进行菌斑、牙垢和牙龈炎评分。在每个周期的第 1、7、14、21 和 27 天测量口气样本中的异味（挥发性硫化合物）。所有犬在整个研究过程中均食用相同的商业干粮。对照组仅提供饮食（CT），而治疗组则在饮食中添加三种牙齿咀嚼物之一。三种新型咀嚼物（Bones & Chews Dental Treats [BC]； Chewy， Inc.，Dania Beach，FL 和 Dr. Lyon's Grain-Free Dental Treats [DL]； Dr. Lyon's，LLC，Dania Beach，FL）和一种领先品牌咀嚼物（Greenies Dental Treats [GR]； Mars Petcare US，Franklin，TN）进行了测试。每天，在饭后 4 小时提供一种咀嚼物。使用 SAS（版本 9.4；SAS Institute， Cary，NC）的混合模型程序分析所有牙齿评分数据。使用 SAS 的混合模型程序分析 Halimeter 数据，并进行处理、时间和处理*时间相互作用差异的测试。数据以 LS 均值±SEM 表示，设 P < 0.05 为统计学显著差异。DL 的表现与领先品牌 GR 一样，因为两者都导致菌斑覆盖和厚度评分、牙垢覆盖评分以及第 27 天挥发性硫浓度降低（P < 0.05）与 CT 相比。此外，与 CT 相比，DL 在第 14 天降低了挥发性硫化合物（P < 0.05）。BC 降低了牙垢覆盖和第 27 天挥发性硫浓度（P < 0.05）与 CT 相比。我们的研究结果表明，本研究中测试的牙齿咀嚼物可能有助于减缓犬牙周病的发展和/或进展。
