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由保宁菌株引起的急性胆管炎 。(原文似乎不完整)

Acute Cholangitis Caused by Boryong Strain of .

作者信息

Lee Keun Hwa, Heo Sang Taek, Jeong Seung Uk, Kim Mi Yeon, Jeong Woo Seong, Hyun Chang Lim, Kim Young Kyu, Yoo Jeong Rae

机构信息

Department of Microbiology, Hanyang University College of Medicine, Seoul, Korea.

Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.

出版信息

Infect Chemother. 2020 Dec;52(4):621-625. doi: 10.3947/ic.2020.52.4.621. Epub 2020 Aug 12.

Abstract

Scrub typhus present with a variety clinical manifestations caused by , it is sometimes accompanied by severe complications. The clinical course of this complication is not well clear. Herein, we first report a case with acute cholangitis and acalculous cholecystitis caused by the Boryong genotype of . A 82-year-old woman presented with fever and acute abdominal pain on the right upper quadrant. Initially, the patient showed an abnormality of liver enzymes of cholestatic pattern. An acute cholangitis and cholecystitis were suspected on the enhanced computed tomography (CT), and emergent endoscopic retrograde cholangiopancreatography (ERCP) performed. However, neither ERCP nor CT detected common bile duct stones or sludge. The patient's illness progressed despite bile drainage and antibiotic therapy. On the fifth day in hospital, an immunofluorescence IgG assay for was positive, and the patient newly developed a skin rash and an eschar lesion on the right abdomen. The polymerase chain reaction amplification of genes from blood and bile was positive, genotype of both samples was identified the Boryong type. The presentation of scrub typhus as an acute cholangitis is not reported till now. In endemic areas, scrub typhus would be considered a rare etiology of acute cholangitis.

摘要

恙虫病可表现出多种由……引起的临床表现,有时还伴有严重并发症。这种并发症的临床过程尚不清楚。在此,我们首次报告一例由博川基因型……引起的急性胆管炎和非结石性胆囊炎病例。一名82岁女性出现发热和右上腹急性腹痛。最初,患者表现出胆汁淤积型肝酶异常。增强计算机断层扫描(CT)怀疑为急性胆管炎和胆囊炎,并进行了紧急内镜逆行胰胆管造影(ERCP)。然而,ERCP和CT均未检测到胆总管结石或胆泥。尽管进行了胆汁引流和抗生素治疗,患者病情仍进展。住院第5天,针对……的免疫荧光IgG检测呈阳性,患者右腹部新出现皮疹和焦痂病变。血液和胆汁中……基因的聚合酶链反应扩增呈阳性,两个样本的基因型均鉴定为博川型。恙虫病表现为急性胆管炎至今尚未见报道。在流行地区,恙虫病应被视为急性胆管炎的罕见病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d04/7779989/292cdf0cbcb0/ic-52-621-g001.jpg

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