Sadeghmousavi Shaghayegh, Rezaei Nima
Neuroimaging Network (NIN), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
SN Compr Clin Med. 2020;2(10):1802-1807. doi: 10.1007/s42399-020-00504-9. Epub 2020 Sep 3.
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to Coronavirus disease 2019 (COVID-19), is not always confined to the respiratory tract, while patients with can develop neurological manifestations. The patients with multiple sclerosis (MS) pose challenges in this pandemic situation, because of the immunosuppressive medications they get and the fact that viral infections may contribute to MS exacerbation and relapses as an environmental factor in genetically predisposed individuals. Herein, possible consequences of COVID-19 which may carry for the MS patients and the underlying mechanisms of its impact are discussed.
感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）会导致2019冠状病毒病（COVID-19），这种感染并不总是局限于呼吸道，患者还可能出现神经症状。在此次疫情中，多发性硬化症（MS）患者面临诸多挑战，这是因为他们服用免疫抑制药物，而且病毒感染作为一种环境因素，可能会促使具有遗传易感性的个体出现MS病情加重和复发。本文将讨论COVID-19对MS患者可能产生的后果及其影响的潜在机制。
