过氧化氢消毒对清洁附着在隐形眼镜上的花粉颗粒有效吗？

Is Hydrogen Peroxide Disinfection Effective for Cleaning Pollen Particles Attached to Contact Lenses?

作者信息

Sunaga Takahiro, Mimura Tatsuya, Matsuoka Hiroshi, Horikawa Hiroaki, Kitsu Kazuma, Mizota Atsushi

机构信息

Department of Ophthalmology, Teikyo University School of Medicine, Itabashi-ku, Tokyo, Japan.

Teikyo University of Science & Technology, Senju Campus 7, Adachi-ku, Tokyo, Japan.

出版信息

Clin Optom (Auckl). 2020 Aug 20;12:123-128. doi: 10.2147/OPTO.S267871. eCollection 2020.

DOI:10.2147/OPTO.S267871

PMID:32904467

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7455597/

Abstract

PURPOSE

It has been proven that wearing soft contact lenses (SCLs) can make pollen-induced allergic conjunctivitis worse. We investigated the cleaning effect of disinfectants and rinsing solution on cedar pollen attached to SCLs.

METHODS

Two-week replacement disposable SCLs, to which pollen particles were experimentally attached, were washed and cleaned with either saline of rinsing solution (n = 10) or 3% hydrogen peroxide (n = 10). We observed, under a microscope, the cedar pollen adhered to the SCLs after washing.

RESULTS

The number of residual pollens attached to SCLs was 23.7 ± 25.7 with rinsing solution and 0.2 ± 0.6 with 3% hydrogen peroxide solution per single area (100 µm × 100 µm). The percentage of adhesion area of pollen to the SCLs was 0.9 ± 1.1% with rinsing solution and 0.0 ± 0.0% with 3% hydrogen peroxide solution. There were significant differences in the number of pollen and adhesion areas of pollen between the two groups (p < 0.05 and p < 0.05, respectively).

CONCLUSION

These results suggest that hydrogen peroxide solution is superior in cleaning effect of cedar pollen attached to SCLs compared to saline.

摘要

目的

已证实佩戴软性隐形眼镜（SCL）会使花粉诱发的过敏性结膜炎病情加重。我们研究了消毒剂和冲洗液对附着在SCL上的雪松花粉的清洁效果。

方法

将实验性附着有花粉颗粒的两周更换型一次性SCL，用冲洗液生理盐水（n = 10）或3%过氧化氢（n = 10）进行清洗。清洗后，在显微镜下观察附着在SCL上的雪松花粉。

结果

每个单位面积（100 µm×100 µm），用冲洗液清洗后附着在SCL上的残留花粉数量为23.7±25.7，用3%过氧化氢溶液清洗后为0.2±0.6。花粉与SCL的附着面积百分比，用冲洗液清洗后为0.9±1.1%，用3%过氧化氢溶液清洗后为0.0±0.0%。两组之间花粉数量和花粉附着面积存在显著差异（分别为p < 0.05和p < 0.05）。