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银的抗菌活性及其在牙科、心脏病学和皮肤病学中的应用。

Antibacterial Activity of Silver and Its Application in Dentistry, Cardiology and Dermatology.

作者信息

Talapko Jasminka, Matijević Tatjana, Juzbašić Martina, Antolović-Požgain Arlen, Škrlec Ivana

机构信息

Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, HR-31000 Osijek, Croatia.

Department of Dermatology and Venereology, Clinical Hospital Center Osijek, HR-31000 Osijek, Croatia.

出版信息

Microorganisms. 2020 Sep 11;8(9):1400. doi: 10.3390/microorganisms8091400.

Abstract

The problem of antimicrobial resistance is increasingly present and requires the discovery of new antimicrobial agents. Although the healing features of silver have been recognized since ancient times, silver has not been used due to newly discovered antibiotics. Thanks to technology development, a significant step forward has been made in silver nanoparticles research. Nowadays, silver nanoparticles are a frequent target of researchers to find new and better drugs. Namely, there is a need for silver nanoparticles as alternative antibacterial nanobiotics. Silver nanoparticles (AgNPs), depending on their size and shape, also have different antimicrobial activity. In addition to their apparent antibacterial activity, AgNPs can serve as drug delivery systems and have anti-thrombogenic, anti-platelet, and anti-hypertensive properties. Today they are increasingly used in clinical medicine and dental medicine. This paper presents silver antimicrobial activity and its use in dentistry, cardiology, and dermatology, where it has an extensive range of effects.

摘要

抗菌耐药性问题日益凸显,需要发现新的抗菌剂。尽管银的治疗特性自古以来就已被认可,但由于新发现的抗生素,银一直未被使用。得益于技术发展,银纳米颗粒研究取得了重大进展。如今,银纳米颗粒是研究人员寻找新型更好药物的常见目标。也就是说,需要银纳米颗粒作为替代抗菌纳米生物制剂。银纳米颗粒(AgNPs)根据其大小和形状,也具有不同的抗菌活性。除了明显的抗菌活性外,AgNPs还可作为药物递送系统,并具有抗血栓形成、抗血小板和抗高血压特性。如今它们在临床医学和牙科医学中越来越常用。本文介绍了银的抗菌活性及其在牙科、心脏病学和皮肤病学中的应用,在这些领域它具有广泛的作用。

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