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孕期及孕前母亲饮酒情况:对母亲及18个月内婴儿结局的影响

Maternal alcohol intakes before and during pregnancy: Impact on the mother and infant outcome to 18 months.

作者信息

McDonald Barry William, Watson Patricia Ellyett

机构信息

Massey University Auckland, New Zealand.

出版信息

Nordisk Alkohol Nark. 2020 Apr;37(2):153-171. doi: 10.1177/1455072520905404. Epub 2020 Mar 9.

DOI:10.1177/1455072520905404
PMID:32934599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7434174/
Abstract

AIM

To investigate maternal alcohol intakes before and during pregnancy, their impact on mothers and infants to 18 months.

METHOD

Prospective study of 504 New Zealand volunteers visited in months 4 and 7 of pregnancy, measurements taken, lifestyle details recorded including alcohol intake before and during pregnancy. Eighteen months after birth, 370 infants were measured, and infant development recorded.

RESULTS

Nineteen per cent of mothers never drank, 53% stopped when they knew they were pregnant, 29% continued to drink. Twenty-two per cent of drinkers binge drank (over 50 g alcohol per session) before pregnancy and 10% during pregnancy. Daily drinking was associated with increased obesity in mothers. Alcohol consumption before or during pregnancy was not associated with infant motor development, had a slight negative effect on growth, and a significant association with vocal ability to 18 months. Energy intake appeared to partially moderate this effect.

CONCLUSION

Maternal alcohol consumption exceeding 50 g per session both before and during pregnancy was associated with decreasing vocal ability in the 18-month old infant.

摘要

目的

调查孕期前后母亲的酒精摄入量及其对母亲和18个月大婴儿的影响。

方法

对504名新西兰志愿者进行前瞻性研究,在孕期第4个月和第7个月进行访视,进行测量,并记录生活方式细节,包括孕期前后的酒精摄入量。婴儿出生18个月后,对370名婴儿进行测量,并记录婴儿发育情况。

结果

19%的母亲从不饮酒,53%在知道自己怀孕后停止饮酒,29%继续饮酒。22%的饮酒者在怀孕前有暴饮行为(每次饮酒超过50克酒精),10%在孕期有暴饮行为。每日饮酒与母亲肥胖增加有关。孕期前后饮酒与婴儿运动发育无关,对生长有轻微负面影响,与18个月大婴儿的发声能力有显著关联。能量摄入似乎部分缓解了这种影响。

结论

孕期前后母亲每次饮酒超过50克与18个月大婴儿的发声能力下降有关。

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