Cattelaens Julia, Turco Laura, Berclaz Luc M, Huelsse Birgit, Hitzl Wolfgang, Vollkommer Tobias, Bodenschatz Karl J
Clinic for Pediatric Surgery, Klinikum Nürnberg Süd, Breslauer Str. 201, 90471 Nuremberg, Germany.
Max-Plank-Institute for Dynamics and Self-Organization, Am Fassberg 17, 37077 Göttingen, Germany.
Life (Basel). 2020 Sep 19;10(9):212. doi: 10.3390/life10090212.
The aim of this retrospective study is to evaluate for the first time the impact of a nanocellulose-based wound dressing in the treatment of pediatric patients with both partial- and deep-thickness burns. Usability and effectiveness were defined based on parameters such as frequency of dressing changes under narcosis, duration of hospital stay, onset of complications, need for additional treatments, and follow up scar formation assessment. Fifty-six children who sustained burns in the year 2018 and were treated with a nanocellulose-based wound dressing were included in the trial. The mean stay in hospital was 6.7 days. Patients underwent dressing changes under narcosis 2.4 times on average, and none had wound-associated infection. In all, 82% of the patients were treated only with nanocellulose-based wound dressings, and reepithelialization occurred after ten days. The majority of patients had scars with normal pigmentation (98%), vascularization (91%), height (92%), and pliability (92%). In conclusion, using a nanocellulose-based wound dressing for the treatment of both superficial, partial-thickness and deep, full-thickness burns has several advantages. Compared with the results published in literature on other wound dressings, it requires a moderate number of dressing changes under narcosis and results in short hospital stays. Additionally, it has a low associated infection rate and promotes wound healing.
这项回顾性研究的目的是首次评估一种基于纳米纤维素的伤口敷料在治疗儿童部分厚度和深度烧伤患者中的效果。可用性和有效性是根据诸如麻醉下换药频率、住院时间、并发症发生情况、额外治疗需求以及随访瘢痕形成评估等参数来定义的。2018年烧伤并接受基于纳米纤维素伤口敷料治疗的56名儿童被纳入该试验。平均住院时间为6.7天。患者平均接受2.4次麻醉下换药，且无一例发生伤口相关感染。总体而言，82%的患者仅接受基于纳米纤维素的伤口敷料治疗，十天后实现了再上皮化。大多数患者的瘢痕色素沉着正常（98%）、血管化正常（91%）、高度正常（92%）且柔韧性正常（92%）。总之，使用基于纳米纤维素的伤口敷料治疗浅表部分厚度和深度全层烧伤具有诸多优势。与文献中关于其他伤口敷料发表的结果相比，它在麻醉下所需的换药次数适中，住院时间短。此外，其感染率低且能促进伤口愈合。
