Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1B 3X9, Canada.
Marine Bioprocessing Facility, Centre of Aquaculture and Seafood Development, Fisheries and Marine Institute, Memorial University of Newfoundland, St. John's, NL A1C 5R3, Canada.
Mar Drugs. 2020 Sep 18;18(9):471. doi: 10.3390/md18090471.
Collagen is the major fibrillar protein in most living organisms. Among the different types of collagen, type I collagen is the most abundant one in tissues of marine invertebrates. Due to the health-related risk factors and religious constraints, use of mammalian derived collagen has been limited. This triggers the search for alternative sources of collagen for both food and non-food applications. In this regard, numerous studies have been conducted on maximizing the utilization of seafood processing by-products and address the need for collagen. However, less attention has been given to marine invertebrates and their by-products. The present review has focused on identifying sea cucumber as a potential source of collagen and discusses the general scope of collagen extraction, isolation, characterization, and physicochemical properties along with opportunities and challenges for utilizing marine-derived collagen.
胶原蛋白是大多数生物体内主要的纤维状蛋白。在不同类型的胶原蛋白中，I 型胶原蛋白是海洋无脊椎动物组织中最丰富的胶原蛋白。由于与健康相关的风险因素和宗教限制，使用哺乳动物来源的胶原蛋白受到限制。这促使人们寻找替代的胶原蛋白来源，包括食品和非食品应用。在这方面，已经进行了大量研究来最大限度地利用海鲜加工副产物，并满足对胶原蛋白的需求。然而，对海洋无脊椎动物及其副产品的关注较少。本综述重点介绍了海参作为胶原蛋白的潜在来源，并讨论了胶原蛋白提取、分离、特性描述以及物理化学性质的一般范围，以及利用海洋衍生胶原蛋白的机会和挑战。
