北方海参():功能性食品、营养保健品和制药领域的潜在候选者。
Northern Sea Cucumber (): A Potential Candidate for Functional Food, Nutraceutical, and Pharmaceutical Sector.
机构信息
Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1B 3X9, Canada.
Marine Bioprocessing Facility, Centre of Aquaculture and Seafood Development, Fisheries and Marine Institute, Memorial University of Newfoundland, St. John's, NL A1C 5R3, Canada.
出版信息
Mar Drugs. 2020 May 22;18(5):274. doi: 10.3390/md18050274.
Sea cucumber () is the most abundant and widely distributed species in the cold waters of North Atlantic Ocean. contains a wide range of bioactive compounds, mainly collagen, cerebrosides, glycosaminoglycan, chondroitin sulfate, saponins, phenols, and mucopolysaccharides, which demonstrate unique biological and pharmacological properties. In particular, the body wall of this marine invertebrate is the major edible part and contains most of the active constituents, mainly polysaccharides and collagen, which exhibit numerous biological activities, including anticancer, anti-hypertensive, anti-angiogenic, anti-inflammatory, antidiabetic, anti-coagulation, antimicrobial, antioxidation, and anti- osteoclastogenic properties. In particular, triterpene glycosides (frondoside A and other) are the most researched group of compounds due to their potential anticancer activity. This review summarizes the latest information on , mainly geographical distribution, landings specific to Canadian coastlines, processing, commercial products, trade market, bioactive compounds, and potential health benefits in the context of functional foods and nutraceuticals.
海参()是北大西洋冷水域中最丰富和分布最广的物种。含有广泛的生物活性化合物,主要有胶原蛋白、脑苷脂、糖胺聚糖、硫酸软骨素、皂苷、酚类和粘多糖,具有独特的生物学和药理学特性。特别是这种海洋无脊椎动物的体壁是主要的可食用部分,含有大多数活性成分,主要是多糖和胶原蛋白,具有多种生物学活性,包括抗癌、抗高血压、抗血管生成、抗炎、抗糖尿病、抗凝血、抗菌、抗氧化、抗破骨细胞生成。特别是三萜糖苷(frondoside A 等)是研究最多的化合物群体,因为它们具有潜在的抗癌活性。本综述总结了有关海参的最新信息,主要包括地理分布、加拿大沿海水域的捕捞情况、加工、商业产品、贸易市场、生物活性化合物以及作为功能性食品和营养保健品的潜在健康益处。