Zhang Qian, Raza Ahmad, Chan Vincent, Minalyan Artem, Madara John
Internal Medicine, Abington Hospital - Jefferson Health, Abington, USA.
Internal Medicine, Abington Hospital- Jefferson Health, Abington, USA.
Cureus. 2020 Aug 19;12(8):e9866. doi: 10.7759/cureus.9866.
Hamman-Rich syndrome is a rapidly progressive interstitial lung disease with acute respiratory distress syndrome physiology. It carries a grave prognosis and a high early mortality rate. It is often distinguished from other similar pulmonary pathologies based on the clinical course, laboratory findings, bronchoalveolar lavage testing, and pathology report. We detail a 77-year-old lady with no prior pulmonary disease, smoking history, or occupational and environmental exposures present to the emergency department found to be in acute hypoxic respiratory failure with impressive progressive radiographic findings. The presumptive diagnosis of Hamman-Rich syndrome was made based on a combination of factors after ruling out other similar clinical entities, especially in the setting of an ongoing COVID-19 pandemic.
哈曼-里奇综合征是一种具有急性呼吸窘迫综合征生理特征的快速进展性间质性肺疾病。其预后严重，早期死亡率高。它通常根据临床病程、实验室检查结果、支气管肺泡灌洗检测和病理报告与其他类似的肺部疾病相鉴别。我们详细介绍一位77岁女性，她既往无肺部疾病、吸烟史，也无职业和环境暴露史，因急性低氧性呼吸衰竭就诊于急诊科，影像学检查发现有明显的进行性改变。在排除其他类似临床疾病后，综合多种因素作出了哈曼-里奇综合征的初步诊断，尤其是在新冠疫情持续的背景下。
