COVID-19 and Pulmonary Coinfection-The First Case Confirmed through Autopsy.

: Establishing the diagnosis of COVID-19 and pulmonary coinfection is difficult due to clinical and radiological similarities that exist between the two disorders. For the moment, fungal coinfections are underestimated in COVID-19 patients. : We report the case of a 52-year-old male patient, who presented to the emergency department for severe dyspnea and died 17 h later. The RT-PCR test performed at his admission was negative for SARS-CoV-2. Retesting of lung fragments collected during autopsy revealed a positive result for SARS-CoV-2. Histopathological examination showed preexisting lesions, due to comorbidities, as well as recent lesions: massive lung thromboses, alveolar exudate rich in foam cells, suprapleural and intra-alveolar cystic forms, and bilateral adrenal hemorrhage. : COVID-19 and coinfection should be considered, particularly in critically ill patients, and we recommend the systematic search for in respiratory samples.