Department of Anatomy and Embryology, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Department of Head and Neck Surgery and Otorhinolaryngology, University Clinical Hospital of Railway Company, Iuliu Hatieganu University of Medicine and Pharmacy, 400015 Cluj-Napoca, Romania.
Medicina (Kaunas). 2021 Mar 24;57(4):302. doi: 10.3390/medicina57040302.
: Establishing the diagnosis of COVID-19 and pulmonary coinfection is difficult due to clinical and radiological similarities that exist between the two disorders. For the moment, fungal coinfections are underestimated in COVID-19 patients. : We report the case of a 52-year-old male patient, who presented to the emergency department for severe dyspnea and died 17 h later. The RT-PCR test performed at his admission was negative for SARS-CoV-2. Retesting of lung fragments collected during autopsy revealed a positive result for SARS-CoV-2. Histopathological examination showed preexisting lesions, due to comorbidities, as well as recent lesions: massive lung thromboses, alveolar exudate rich in foam cells, suprapleural and intra-alveolar cystic forms, and bilateral adrenal hemorrhage. : COVID-19 and coinfection should be considered, particularly in critically ill patients, and we recommend the systematic search for in respiratory samples.
：由于 COVID-19 和肺部合并感染这两种疾病在临床和影像学上存在相似之处，因此很难确诊 COVID-19 和肺部合并感染。目前，COVID-19 患者的真菌感染合并感染被低估了。：我们报告了一例 52 岁男性患者的病例，他因严重呼吸困难到急诊科就诊，17 小时后死亡。他入院时进行的 RT-PCR 检测 SARS-CoV-2 结果为阴性。对尸检时采集的肺组织碎片进行的重新检测显示 SARS-CoV-2 检测结果为阳性。组织病理学检查显示存在由于合并症引起的先前病变以及最近的病变：大量肺血栓形成、富含泡沫细胞的肺泡渗出物、胸膜上和肺泡内的囊性病变以及双侧肾上腺出血。：COVID-19 和合并感染应予以考虑，特别是在重症患者中，我们建议系统地在呼吸道样本中寻找。
