Pepose J S, MacRae S, Quinn T C, Ward J W
Am J Ophthalmol. 1987 Jun 15;103(6):798-801. doi: 10.1016/s0002-9394(14)74396-x.
Four corneas from two cadavers that later had positive test results on enzyme-linked immunosorbent assays and Western blot analysis for antibodies against the human immunodeficiency virus were inadvertently transplanted to recipients who were without known risk of human immunodeficiency virus infection. We performed serial studies of serologic markers of human immunodeficiency virus infection in the cornea recipients and assayed reverse transcriptase levels of their mixed lymphocyte cultures. The four cornea transplant recipients were followed up for 130, 152, 397, and 440 days, respectively, and the results on all serologic tests and reverse transcriptase assays remain negative.
来自两名尸体捐赠者的四只角膜，后来在酶联免疫吸附测定和蛋白质印迹分析中检测出抗人类免疫缺陷病毒抗体呈阳性，这些角膜被意外移植给了无已知人类免疫缺陷病毒感染风险的接受者。我们对角膜接受者进行了人类免疫缺陷病毒感染血清学标志物的系列研究，并检测了他们混合淋巴细胞培养物中的逆转录酶水平。四名角膜移植接受者分别随访了130天、152天、397天和440天，所有血清学检测和逆转录酶测定结果均为阴性。
