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NOD2-dependent BCG-induced trained immunity: A way to regulate innate responses to SARS-CoV2?

作者信息

Wannigama Dhammika Leshan, Jacquet Alain

机构信息

Department of Microbiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand; Antimicrobial Resistance and Stewardship Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; School of Medicine, Faculty of Health and Medical Sciences, The University of Western Australia, Nedlands, Western Australia, Australia.

Center of Excellence in Vaccine Research and Development, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

Int J Infect Dis. 2020 Dec;101:52-55. doi: 10.1016/j.ijid.2020.09.1429. Epub 2020 Sep 24.

DOI:10.1016/j.ijid.2020.09.1429
PMID:32980554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7832069/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3402/7832069/a9017b24b908/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3402/7832069/0bee11b750b0/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3402/7832069/a9017b24b908/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3402/7832069/0bee11b750b0/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3402/7832069/a9017b24b908/gr2_lrg.jpg

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本文引用的文献

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2
Dysregulation of type I interferon responses in COVID-19.COVID-19 中 I 型干扰素反应失调。
Nat Rev Immunol. 2020 Jul;20(7):397-398. doi: 10.1038/s41577-020-0346-x. Epub 2020 May 26.
3
BCG-induced trained immunity: can it offer protection against COVID-19?BCG 诱导的训练免疫:能提供针对 COVID-19 的保护吗?
一项系统评价和荟萃分析,研究了氟伏沙明治疗 COVID-19 病情恶化、死亡和长期 COVID 并发症的剂量和时间疗效。
Sci Rep. 2024 Jun 12;14(1):13462. doi: 10.1038/s41598-024-64260-9.
4
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EClinicalMedicine. 2024 Mar 14;70:102517. doi: 10.1016/j.eclinm.2024.102517. eCollection 2024 Apr.
5
Research progress on specific and non-specific immune effects of BCG and the possibility of BCG protection against COVID-19.BCG 对 COVID-19 的特异性和非特异性免疫作用及其保护作用的研究进展。
Front Immunol. 2023 Jan 31;14:1118378. doi: 10.3389/fimmu.2023.1118378. eCollection 2023.
6
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10
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