Department of Psychiatry, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Department of Public Health, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Neuropsychopharmacol Rep. 2021 Mar;41(1):50-55. doi: 10.1002/npr2.12154. Epub 2020 Dec 17.
Individuals infected by the novel coronavirus (SARS-CoV-2) have experienced different psychiatric manifestations during the period of infectivity and post-COVID-19 infection. Fatigue and anhedonia are among the frequently reported manifestations after recovery from this novel viral pandemic, leading to early evaluation of those patients and proper management of their complaints which have a drastic burden on different domains of life. Also, the period after recovery might have an effect on the severity of these two psychiatric presentations.
This cross-sectional observational study aimed to investigate the occurrence of post-COVID-19 fatigue and anhedonia and whether the duration after 2 consecutive PCR-negative tests has an implication on the severity of the above-mentioned psychiatric manifestations.
Socio-demographic characteristics of 200 post-COVID-19 patients were collected, and also, the self-assessment anhedonia scale was used to evaluate the degree of anhedonia. Fatigue assessment scale used to investigate this domain. The study targeted to find a possible correlation between the period after recovery and the other variables including anhedonia and fatigue.
The study revealed high scores of different subtypes of self-assessment anhedonia scale (including total intensity, total frequency, and total changes scores) in the studied group, also high score of fatigue assessment scale in those patients. Positive statistically significant correlation between anhedonia and fatigue in post-COVID-19 group, also negative statistically significant correlation between duration after recovery and the other 2 variables(anhedonia and fatigue) in the examined patients.
Post-COVID-19 fatigue and anhedonia were prevalent and commonly reported in the post-COVID-19 period, also the duration after 2 consecutive negative PCR tests has an implication on the severity rating scale of both anhedonia and fatigue. These findings directed our attention to those reported manifestations which affected the socio-occupational functioning of the individuals during this whole world pandemic.
新型冠状病毒（SARS-CoV-2）感染个体在感染期和新冠病毒感染后经历了不同的精神表现。在这种新型病毒性大流行康复后，疲劳和快感缺失是经常报告的表现之一，这导致对这些患者进行早期评估和对其投诉进行适当管理，这对生活的不同领域都有巨大的影响。此外，康复后的时期可能会对这两种精神表现的严重程度产生影响。
这项横断面观察性研究旨在调查新冠病毒感染后疲劳和快感缺失的发生情况，以及连续两次 PCR 阴性检测后持续时间是否对上述精神表现的严重程度有影响。
收集了 200 名新冠病毒感染后患者的社会人口统计学特征，还使用自我评估快感缺失量表评估快感缺失程度。使用疲劳评估量表来调查这一领域。该研究旨在寻找康复后时期与包括快感缺失和疲劳在内的其他变量之间的可能相关性。
研究显示，研究组中不同亚型的自我评估快感缺失量表（包括总强度、总频率和总变化评分）得分较高，患者的疲劳评估量表得分也较高。新冠病毒感染后组中快感缺失和疲劳之间存在正显著相关性，在检查患者中，康复后时期与其他 2 个变量（快感缺失和疲劳）之间存在负显著相关性。
新冠病毒感染后疲劳和快感缺失在新冠病毒感染后时期普遍存在且经常报告，连续两次 PCR 阴性检测后的持续时间对快感缺失和疲劳的严重程度评分有影响。这些发现引起了我们对在整个世界大流行期间影响个体社会职业功能的这些报告表现的关注。
