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中药注射剂对重症肺炎的影响:一项系统评价与Meta分析方案

Effect of traditional Chinese medicine injections on severe pneumonia: A protocol for systematic review and meta-analysis.

作者信息

Luo Wei, Liu Ya, Zhang Qiang, Zhong Huifang, Deng Jia

机构信息

Department of Respiratory and Critical Care Medicine, Chongqing Jiangbei Hospital of Traditional Chinese Medicine.

Department of Dermatology, Chongqing Hospital of Traditional Chinese Medicine.

出版信息

Medicine (Baltimore). 2020 Sep 25;99(39):e22012. doi: 10.1097/MD.0000000000022012.

Abstract

BACKGROUND

Traditional Chinese medicine injections (TCMJ) used in the treatment of severe pneumonia have been widely implemented in clinical practice, but their overall efficacy and safety remain unclear. This paper aims to evaluate the efficacy and safety of TCMJ in the treatment of severe pneumonia.

METHODS

PubMed, EMbase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, WanFang, and the Chongqing VIP Chinese Science and Technology Periodical Database were all searched for randomized controlled trials focusing on the administration of TCMJ for severe pneumonia. Two researchers independently screened titles, abstracts, full texts, and extracted relevant data. The RevMan 5.3 software (The Cochrane Collaboration, Software Update, Oxford, UK) and Stata 14 software (STATA Corporation, College Station, TX) were used for statistical analysis.

RESULTS

This study summarizes the related randomized controlled trials to assess the effect and safety of TCMJ in the treatment of severe pneumonia.

CONCLUSION

This article provides theoretical support for the clinical application of TCMJ in the treatment of severe pneumonia.

PROSPERO REGISTRATION NUMBER

CRD42020185072.

摘要

背景

用于治疗重症肺炎的中药注射剂在临床实践中已广泛应用,但其总体疗效和安全性仍不明确。本文旨在评估中药注射剂治疗重症肺炎的疗效和安全性。

方法

检索了PubMed、EMbase、Cochrane图书馆、Web of Science、中国知网、万方和重庆维普中文科技期刊数据库,以查找聚焦于使用中药注射剂治疗重症肺炎的随机对照试验。两名研究人员独立筛选标题、摘要、全文,并提取相关数据。使用RevMan 5.3软件(英国牛津Cochrane协作网软件更新公司)和Stata 14软件(美国德克萨斯州大学站STATA公司)进行统计分析。

结果

本研究总结了相关随机对照试验,以评估中药注射剂治疗重症肺炎的效果和安全性。

结论

本文为中药注射剂治疗重症肺炎的临床应用提供了理论支持。

国际前瞻性系统评价注册编号

CRD42020185072。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fc6/7523816/479b0e3273b2/medi-99-e22012-g002.jpg

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