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Comparing the impact of targeting limited driving pressure to low tidal volume ventilation on mortality in mechanically ventilated adults with COVID-19 ARDS: an exploratory target trial emulation.比较针对限定驱动压与低潮气量通气对 COVID-19 相关急性呼吸窘迫综合征机械通气成人死亡率影响的探索性目标模拟试验。
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本文引用的文献

1
High Pleural Pressure Prevents Alveolar Overdistension and Hemodynamic Collapse in Acute Respiratory Distress Syndrome with Class III Obesity. A Clinical Trial.高胸腔压力可预防 III 类肥胖急性呼吸窘迫综合征的肺泡过度膨胀和血液动力学崩溃。一项临床试验。
Am J Respir Crit Care Med. 2021 Mar 1;203(5):575-584. doi: 10.1164/rccm.201909-1687OC.
2
Value of measuring esophageal pressure to evaluate heart-lung interactions-applications for invasive hemodynamic monitoring.测量食管压力以评估心肺相互作用在有创血流动力学监测中的应用价值。
Ann Transl Med. 2018 Sep;6(18):351. doi: 10.21037/atm.2018.05.04.
3
Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.肺复张与滴定式呼气末正压通气(PEEP)对比低PEEP对急性呼吸窘迫综合征患者死亡率的影响:一项随机临床试验
JAMA. 2017 Oct 10;318(14):1335-1345. doi: 10.1001/jama.2017.14171.
4
Driving pressure and survival in the acute respiratory distress syndrome.驱动压与急性呼吸窘迫综合征患者的生存。
N Engl J Med. 2015 Feb 19;372(8):747-55. doi: 10.1056/NEJMsa1410639.
5
Prevalence and trends in obesity among US adults, 1999-2008.美国成年人肥胖率的流行趋势及变化,1999-2008 年。
JAMA. 2010 Jan 20;303(3):235-41. doi: 10.1001/jama.2009.2014. Epub 2010 Jan 13.
6
Obesity and the lung: 3. Obesity, respiration and intensive care.肥胖与肺部:3. 肥胖、呼吸与重症监护。
Thorax. 2008 Oct;63(10):925-31. doi: 10.1136/thx.2007.086835.
7
ARDSnet ventilatory protocol and alveolar hyperinflation: role of positive end-expiratory pressure.急性呼吸窘迫综合征网络通气方案与肺泡过度充气:呼气末正压的作用
Am J Respir Crit Care Med. 2007 Oct 15;176(8):761-7. doi: 10.1164/rccm.200702-193OC. Epub 2007 Jul 26.
8
The oxygen delivery/consumption controversy. Approaches to management of the critically ill.氧输送/氧消耗争议。危重症患者的管理方法。
Am J Respir Crit Care Med. 1994 Feb;149(2 Pt 1):533-7. doi: 10.1164/ajrccm.149.2.8306058.

Mechanical Ventilation in the Obese Patient: Compliance, Pleural Pressure, and Driving Pressure.

作者信息

Magder Sheldon, Slobod Douglas, Assanangkornchai Nawaporn

机构信息

McGill University Health Centre Montreal, Quebec, Canada.

出版信息

Am J Respir Crit Care Med. 2021 Mar 1;203(5):534-536. doi: 10.1164/rccm.202009-3607ED.

DOI:10.1164/rccm.202009-3607ED
PMID:32997946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7924569/
Abstract
摘要