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衰老及衰老相关疾病中的细胞外囊泡与细胞外RNA

Extracellular vesicles and extracellular RNA in aging and age-related disease.

作者信息

Noren Hooten Nicole

机构信息

Laboratory of Epidemiology and Population Science, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD, 21224, USA.

出版信息

Transl Med Aging. 2020;4:96-98. doi: 10.1016/j.tma.2020.07.006. Epub 2020 Jul 24.

Abstract

Circulating factors are well known to influence aging and age-related disease. As part of the Aging Science Talks: Science for the Community series, data was presented on two types of circulating functional biomarkers: extracellular RNA (exRNA) and extracellular vesicles (EVs). EVs in the context of type 2 diabetes mellitus was also discussed, as this is an area of interest due to the growing global epidemic of this age-related disease.

摘要

众所周知,循环因子会影响衰老及与年龄相关的疾病。作为“衰老科学讲座:面向社区的科学”系列活动的一部分,会上展示了关于两种循环功能性生物标志物的数据:细胞外RNA(exRNA)和细胞外囊泡(EV)。会上还讨论了2型糖尿病背景下的细胞外囊泡,鉴于这种与年龄相关的疾病在全球范围内日益流行,这是一个备受关注的领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba8c/7526621/97aa78af9cca/nihms-1631631-f0001.jpg

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