Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Independent Researcher, Tehran, Iran.
Radiol Med. 2021 Jan;126(1):40-46. doi: 10.1007/s11547-020-01295-8. Epub 2020 Oct 1.
The long-term sequelae of coronavirus disease 2019 (COVID-19) are still unknown. Lessons from past viral epidemics reveal that, after recovery, patients with viral pulmonary infections can suffer from irreversible pulmonary dysfunction and demonstrate residual imaging or functional abnormalities. Residual ground glass opacities, consolidations, reticular and linear opacities, residual crazy paving pattern, melted sugar sign, and parenchymal fibrotic bands are several features found in the late or remission stages of COVID-19. These radiologic findings have been observed weeks after symptom onset, even after hospital discharge, and they may or may not correlate with clinical manifestations. High-resolution CT may be indicated to establish new baselines and track changes in residual impairments. In our previous review, we observed significant pulmonary sequelae in some COVID-19 survivors at follow-up. In this update, we review the current literature on the clinical and radiologic manifestations of post-recovery COVID-19 toward the end of hospital admission and after discharge.
新型冠状病毒疾病 2019(COVID-19)的长期后遗症仍不清楚。从过去的病毒流行中吸取的教训表明,病毒性肺部感染患者在康复后可能会遭受不可逆转的肺功能障碍,并表现出残留的影像学或功能异常。在 COVID-19 的晚期或缓解阶段,可以发现残留的磨玻璃影、实变、网状和线状影、残留的杂乱铺路模式、糖融化征和实质纤维性带等特征。这些影像学发现可在症状出现数周后,甚至在出院后观察到,且它们可能与临床表现相关,也可能不相关。高分辨率 CT 可能有助于确定新的基线,并跟踪残留损害的变化。在我们之前的综述中,我们观察到一些 COVID-19 幸存者在随访中有明显的肺部后遗症。在本次更新中,我们回顾了住院期间和出院后 COVID-19 康复后患者的临床和影像学表现的现有文献。