Gasparik A, Demián M B, Pascanu I
University of Medicine Pharmacy Science and Technology of Targu Mures - Public Health, Targu Mures, Romania.
University of Medicine Pharmacy Science and Technology of Targu Mures - Endocrinology, Targu Mures, Romania.
Acta Endocrinol (Buchar). 2020 Apr-Jun;16(2):216-222. doi: 10.4183/aeb.2020.216.
Several studies have addressed the impact of sarcopenia on various health outcomes. As the most critical issue is the early identification of individuals, a short screening tool may help clinicians to simply test for sarcopenia and start early management of the disease. Recently, a simple questionnaire, Sarc-F was provided that may adequately realize this aim.
To validate the questionnaire we translated the original Sarc-F according to the recommended methodology. A total of 80 people, aged 65+ were evaluated for sarcopenia. Muscle mass, strength, and physical performance were measured. Volunteers completed the Sarc-F as well as other two questionnaires. Discriminative power, reliability, construct validity analyses, specificity, sensitivity, negative and positive predictive value evaluations were made.
A good discriminative power and internal consistency were found. With the functional sarcopenia diagnostic criteria the test demonstrates a high specificity (84%). The positive and negative predictive values were: 78% and 77%. Using the more conservative diagnostic criteria the negative predictive value was: 85.4%, sufficient to rule out those not at risk of having sarcopenia and eliminate the need for further investigations.
A valid Romanian Sarc-F questionnaire is now available to simply detect patients at risk/no risk of sarcopenia.
多项研究探讨了肌肉减少症对各种健康结局的影响。由于最关键的问题是个体的早期识别，一种简短的筛查工具可能有助于临床医生简单地检测肌肉减少症并尽早开始对该疾病的管理。最近，提供了一种简单的问卷Sarc-F，它可能充分实现这一目标。
为了验证该问卷，我们根据推荐的方法对原始的Sarc-F进行了翻译。总共对80名65岁及以上的人进行了肌肉减少症评估。测量了肌肉质量、力量和身体表现。志愿者完成了Sarc-F以及其他两份问卷。进行了判别力、可靠性、结构效度分析、特异性、敏感性、阴性和阳性预测值评估。
发现具有良好的判别力和内部一致性。根据功能性肌肉减少症诊断标准，该测试显示出较高的特异性（84%）。阳性和阴性预测值分别为：78%和77%。使用更保守的诊断标准，阴性预测值为：85.4%，足以排除那些没有肌肉减少症风险的人，无需进一步检查。
现在有一个有效的罗马尼亚语Sarc-F问卷，可用于简单地检测有/无肌肉减少症风险的患者。
